ID OPGH_SHEPC Reviewed; 727 AA.
AC A4Y768;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072};
GN OrderedLocusNames=Sputcn32_2080;
OS Shewanella putrefaciens (strain CN-32 / ATCC BAA-453).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=319224;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CN-32 / ATCC BAA-453;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Fredrickson J.,
RA Tiedje J., Richardson P.;
RT "Complete sequence of Shewanella putrefaciens CN-32.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01072}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR EMBL; CP000681; ABP75801.1; -; Genomic_DNA.
DR AlphaFoldDB; A4Y768; -.
DR STRING; 319224.Sputcn32_2080; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR KEGG; spc:Sputcn32_2080; -.
DR eggNOG; COG2943; Bacteria.
DR HOGENOM; CLU_015730_1_0_6; -.
DR UniPathway; UPA00637; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd04191; Glucan_BSP_MdoH; 1.
DR HAMAP; MF_01072; MdoH_OpgH; 1.
DR InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF5; GLUCANS BIOSYNTHESIS GLUCOSYLTRANSFERASE H; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..727
FT /note="Glucans biosynthesis glucosyltransferase H"
FT /id="PRO_1000084503"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 460..480
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 496..516
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 572..592
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT REGION 18..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 80798 MW; 0CEEB3BBD931B108 CRC64;
MTVSENSVLE TEVLVGGSAM PNERPGAMEP QSLTEMPEGF PRRSTVANGV RSRSSRRFFV
VGGALLLSSF AIYEMGAVFS IGGITPLEYL VLLLFAINFC WIALAFCSGI AGFLILLRKP
KAKDLEVTEL HTRTAILMPT YNESPDRVFS AVSVMAEALS QTGHGHAFDW FILSDTTDPE
IALLEEQAFL VLRQETHKHS RVYYRRRRKN VARKAGNVAD FCRRWGSRYD HLLVLDADSL
MESSTITGLA QRMQADPDAG LIQTIPSLIN GTTLMARLQQ FAARIYGPVI GTGLGWWVQK
EGNFWGHNAI IRTEAFMGAA GLPNLKGKPP FGGHILSHDF VEAALIRRAG WSVVIAYDLP
GSYEECPPSI VDLAVRDRRW CQGNLQHSRI LPTKGLHWVS RLHLLTGIMA YLSSPFWLLL
ILTGLMLALQ AHFIRPEYFT DQFSLFPTWP IMDSDRALRL FYITMGVLFG PKIFGVLLLL
KDGQFARSVG GRIKAIFSVL FEVVLSALIA PIMMFIHCGA VMSILMGRDS GWSPQRRDDG
SMPWLTLIYR HRWHMLAGVM LGYAAILDSL TLLAWMSPAL IGLWFAVPIS AWTGSVKIGE
VFKRAGILAT PEERSPAAIC LQAQDARAAY QAHISKPWTL AQLLKDPALM ELHLAMVDKQ
PLRAAGTPIE PVEAIVHVKV HEAQCQESAM ALFNRQEMAL VLANPLMLRS LQKLPEQFVA
EDLVSFC
//
