ID KPPR_ECOLI Reviewed; 289 AA.
AC P0AEX5; P37307; P76684; Q2M721;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 01-MAY-2013, entry version 58.
DE RecName: Full=Probable phosphoribulokinase;
DE Short=PRK;
DE Short=PRKase;
DE EC=2.7.1.19;
DE AltName: Full=Phosphopentokinase;
GN Name=prkB; Synonyms=yhfF; OrderedLocusNames=b3355, JW3318;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA Mau B., Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1474(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains
RT MG1655 and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 228-289.
RC STRAIN=K12;
RX PubMed=1756168; DOI=10.1016/0167-4781(91)90222-8;
RA Bhasin R., Freundlich M.;
RT "The nucleotide sequence of the Escherichia coli crp divergent RNA and
RT an overlapping ORF.";
RL Biochim. Biophys. Acta 1129:109-111(1991).
RN [4]
RP IDENTIFICATION.
RX PubMed=7940673; DOI=10.1016/0968-0004(94)90067-1;
RA Borodovsky M., Koonin E.V., Rudd K.E.;
RT "New genes in old sequence: a strategy for finding genes in the
RT bacterial genome.";
RL Trends Biochem. Sci. 19:309-313(1994).
RN [5]
RP IDENTIFICATION.
RX PubMed=7984428; DOI=10.1093/nar/22.22.4756;
RA Borodovsky M., Rudd K.E., Koonin E.V.;
RT "Intrinsic and extrinsic approaches for detecting genes in a bacterial
RT genome.";
RL Nucleic Acids Res. 22:4756-4767(1994).
RN [6]
RP IDENTIFICATION.
RX PubMed=7920643; DOI=10.1038/ng0694-205;
RA Robison K., Gilbert W., Church G.M.;
RT "Large scale bacterial gene discovery by similarity search.";
RL Nat. Genet. 7:205-214(1994).
CC -!- CATALYTIC ACTIVITY: ATP + D-ribulose 5-phosphate = ADP + D-
CC ribulose 1,5-bisphosphate.
CC -!- SIMILARITY: Belongs to the phosphoribulokinase family.
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DR EMBL; U18997; AAA58152.1; ALT_FRAME; Genomic_DNA.
DR EMBL; U00096; AAC76380.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77935.1; -; Genomic_DNA.
DR EMBL; X61919; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; F65129; F65129.
DR RefSeq; NP_417814.1; NC_000913.2.
DR RefSeq; YP_492076.1; NC_007779.1.
DR ProteinModelPortal; P0AEX5; -.
DR SMR; P0AEX5; 2-288.
DR IntAct; P0AEX5; 4.
DR MINT; MINT-1286728; -.
DR STRING; 511145.b3355; -.
DR PaxDb; P0AEX5; -.
DR PRIDE; P0AEX5; -.
DR EnsemblBacteria; AAC76380; AAC76380; b3355.
DR EnsemblBacteria; BAE77935; BAE77935; BAE77935.
DR GeneID; 12930596; -.
DR GeneID; 947862; -.
DR KEGG; ecj:Y75_p3820; -.
DR KEGG; eco:b3355; -.
DR PATRIC; 32122144; VBIEscCol129921_3449.
DR EchoBASE; EB2268; -.
DR EcoGene; EG12365; prkB.
DR eggNOG; COG3954; -.
DR HOGENOM; HOG000272991; -.
DR KO; K00855; -.
DR OMA; LGRHISY; -.
DR ProtClustDB; PRK15453; -.
DR BioCyc; EcoCyc:EG12365-MONOMER; -.
DR BioCyc; ECOL316407:JW3318-MONOMER; -.
DR Genevestigator; P0AEX5; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008974; F:phosphoribulokinase activity; IEA:EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR InterPro; IPR006082; PRK.
DR InterPro; IPR006083; PRK/URK.
DR Pfam; PF00485; PRK; 1.
DR PRINTS; PR00478; PHRIBLKINASE.
DR PROSITE; PS00567; PHOSPHORIBULOKINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW Reference proteome; Transferase.
FT CHAIN 1 289 Probable phosphoribulokinase.
FT /FTId=PRO_0000201952.
FT NP_BIND 12 20 ATP (By similarity).
FT CONFLICT 250 250 Q -> L (in Ref. 3).
SQ SEQUENCE 289 AA; 32344 MW; A98EE1A322148DAE CRC64;
MSAKHPVIAV TGSSGAGTTT TSLAFRKIFA QLNLHAAEVE GDSFHRYTRP EMDMAIRKAR
DAGRHISYFG PEANDFGLLE QTFIEYGQSG KGKSRKYLHT YDEAVPWNQV PGTFTPWQPL
PEPTDVLFYE GLHGGVVTPQ HNVAQHVDLL VGVVPIVNLE WIQKLIRDTS ERGHSREAVM
DSVVRSMEDY INYITPQFSR THLNFQRVPT VDTSNPFAAK GIPSLDESFV VIHFRNLEGI
DFPWLLAMLQ GSFISHINTL VVPGGKMGLA MELIMLPLVQ RLMEGKKIE
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