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Database: UniProt
Entry: P22330
LinkDB: P22330
Original site: P22330 
ID   OPSG1_ASTFA             Reviewed;         355 AA.
AC   P22330;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   01-OCT-2014, entry version 79.
DE   RecName: Full=Green-sensitive opsin-1;
DE   AltName: Full=Green cone photoreceptor pigment 1;
GN   Name=G103; Synonyms=GF;
OS   Astyanax fasciatus (Blind cave fish) (Astyanax mexicanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Characidae; Characidae incertae sedis; Astyanax clade;
OC   Astyanax.
OX   NCBI_TaxID=223369;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Pineal gland;
RX   PubMed=2385921; DOI=10.1016/0042-6989(90)90049-Q;
RA   Yokoyama R., Yokoyama S.;
RT   "Isolation, DNA sequence and evolution of a color visual pigment gene
RT   of the blind cave fish Astyanax fasciatus.";
RL   Vision Res. 30:807-816(1990).
CC   -!- FUNCTION: Visual pigments are the light-absorbing molecules that
CC       mediate vision. They consist of an apoprotein, opsin, covalently
CC       linked to cis-retinal.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: The color pigments are found in the cone
CC       photoreceptor cells.
CC   -!- MISCELLANEOUS: This fish possesses three genes for green opsin.
CC       Two (G103 and G101) that belong to the LWS/MWS group and one
CC       (RH11) that belongs to the RH2 group.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Opsin subfamily. {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; M60945; AAA48545.1; -; Genomic_DNA.
DR   EMBL; M60938; AAA48545.1; JOINED; Genomic_DNA.
DR   EMBL; M60939; AAA48545.1; JOINED; Genomic_DNA.
DR   EMBL; M60940; AAA48545.1; JOINED; Genomic_DNA.
DR   EMBL; M60943; AAA48545.1; JOINED; Genomic_DNA.
DR   EMBL; M60944; AAA48545.1; JOINED; Genomic_DNA.
DR   EMBL; U12025; AAA67216.1; -; Genomic_DNA.
DR   PIR; I50091; I50091.
DR   ProteinModelPortal; P22330; -.
DR   HOVERGEN; HBG107442; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1070.10; -; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR001760; Opsin.
DR   InterPro; IPR000378; Opsin_red/grn.
DR   InterPro; IPR027430; Retinal_BS.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00238; OPSIN.
DR   PRINTS; PR00575; OPSINREDGRN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   PROSITE; PS00238; OPSIN; 1.
PE   1: Evidence at protein level;
KW   Chromophore; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Phosphoprotein; Photoreceptor protein; Receptor;
KW   Retinal protein; Sensory transduction; Transducer; Transmembrane;
KW   Transmembrane helix; Vision.
FT   CHAIN         1    355       Green-sensitive opsin-1.
FT                                /FTId=PRO_0000197772.
FT   TOPO_DOM      1     49       Extracellular. {ECO:0000255}.
FT   TRANSMEM     50     74       Helical; Name=1. {ECO:0000255}.
FT   TOPO_DOM     75     86       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     87    112       Helical; Name=2. {ECO:0000255}.
FT   TOPO_DOM    113    126       Extracellular. {ECO:0000255}.
FT   TRANSMEM    127    146       Helical; Name=3. {ECO:0000255}.
FT   TOPO_DOM    147    165       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    166    189       Helical; Name=4. {ECO:0000255}.
FT   TOPO_DOM    190    215       Extracellular. {ECO:0000255}.
FT   TRANSMEM    216    243       Helical; Name=5. {ECO:0000255}.
FT   TOPO_DOM    244    265       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    266    289       Helical; Name=6. {ECO:0000255}.
FT   TOPO_DOM    290    297       Extracellular. {ECO:0000255}.
FT   TRANSMEM    298    322       Helical; Name=7. {ECO:0000255}.
FT   TOPO_DOM    323    355       Cytoplasmic. {ECO:0000255}.
FT   MOD_RES     309    309       N6-(retinylidene)lysine.
FT   CARBOHYD     31     31       N-linked (GlcNAc...). {ECO:0000255}.
FT   DISULFID    123    200       {ECO:0000255|PROSITE-ProRule:PRU00521}.
SQ   SEQUENCE   355 AA;  39696 MW;  9B7B6B8F361BCDA2 CRC64;
     MAAHADEPVF AARRYNEETT RESAFVYTNA NNTRDPFEGP NYHIAPRWVY NLASLWMIIV
     VIASIFTNSL VIVATAKFKK LRHPLNWILV NLAIADLGET VLASTISVFN QVFGYFVLGH
     PMCIFEGWTV SVCGITALWS LTIISWERWV VVCKPFGNVK FDGKWAAGGI IFAWTWAIIW
     CTPPIFGWSR YWPHGLKTSC GPDVFSGSED PGVASYMVTL LLTCCILPLS VIIICYIFVW
     NAIHQVAQQQ KDSESTQKAE KEVSRMVVVM ILAFILCWGP YASFATFSAL NPGYAWHPLA
     AALPAYFAKS ATIYNPIIYV FMNRQFRSCI MQLFGKKVED ASEVSGSTTE VSTAS
//
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