ID OPSG1_ASTFA Reviewed; 355 AA.
AC P22330;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1991, sequence version 1.
DT 03-APR-2013, entry version 74.
DE RecName: Full=Green-sensitive opsin-1;
DE AltName: Full=Green cone photoreceptor pigment 1;
GN Name=G103; Synonyms=GF;
OS Astyanax fasciatus (Blind cave fish) (Astyanax mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characidae; Characidae incertae sedis; Astyanax clade; Astyanax.
OX NCBI_TaxID=223369;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Pineal gland;
RX PubMed=2385921; DOI=10.1016/0042-6989(90)90049-Q;
RA Yokoyama R., Yokoyama S.;
RT "Isolation, DNA sequence and evolution of a color visual pigment gene
RT of the blind cave fish Astyanax fasciatus.";
RL Vision Res. 30:807-816(1990).
CC -!- FUNCTION: Visual pigments are the light-absorbing molecules that
CC mediate vision. They consist of an apoprotein, opsin, covalently
CC linked to cis-retinal.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: The color pigments are found in the cone
CC photoreceptor cells.
CC -!- MISCELLANEOUS: This fish possesses three genes for green opsin.
CC Two (G103 and G101) that belong to the LWS/MWS group and one
CC (RH11) that belongs to the RH2 group.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC Opsin subfamily.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; M60945; AAA48545.1; -; Genomic_DNA.
DR EMBL; M60938; AAA48545.1; JOINED; Genomic_DNA.
DR EMBL; M60939; AAA48545.1; JOINED; Genomic_DNA.
DR EMBL; M60940; AAA48545.1; JOINED; Genomic_DNA.
DR EMBL; M60943; AAA48545.1; JOINED; Genomic_DNA.
DR EMBL; M60944; AAA48545.1; JOINED; Genomic_DNA.
DR EMBL; U12025; AAA67216.1; -; Genomic_DNA.
DR PIR; I50091; I50091.
DR ProteinModelPortal; P22330; -.
DR HOVERGEN; HBG107442; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001760; Opsin.
DR InterPro; IPR000378; Opsin_red/grn.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00238; OPSIN.
DR PRINTS; PR00575; OPSINREDGRN.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS00238; OPSIN; 1.
PE 1: Evidence at protein level;
KW Chromophore; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Phosphoprotein; Photoreceptor protein; Receptor;
KW Retinal protein; Sensory transduction; Transducer; Transmembrane;
KW Transmembrane helix; Vision.
FT CHAIN 1 355 Green-sensitive opsin-1.
FT /FTId=PRO_0000197772.
FT TOPO_DOM 1 49 Extracellular (Potential).
FT TRANSMEM 50 74 Helical; Name=1; (Potential).
FT TOPO_DOM 75 86 Cytoplasmic (Potential).
FT TRANSMEM 87 112 Helical; Name=2; (Potential).
FT TOPO_DOM 113 126 Extracellular (Potential).
FT TRANSMEM 127 146 Helical; Name=3; (Potential).
FT TOPO_DOM 147 165 Cytoplasmic (Potential).
FT TRANSMEM 166 189 Helical; Name=4; (Potential).
FT TOPO_DOM 190 215 Extracellular (Potential).
FT TRANSMEM 216 243 Helical; Name=5; (Potential).
FT TOPO_DOM 244 265 Cytoplasmic (Potential).
FT TRANSMEM 266 289 Helical; Name=6; (Potential).
FT TOPO_DOM 290 297 Extracellular (Potential).
FT TRANSMEM 298 322 Helical; Name=7; (Potential).
FT TOPO_DOM 323 355 Cytoplasmic (Potential).
FT MOD_RES 309 309 N6-(retinylidene)lysine.
FT CARBOHYD 31 31 N-linked (GlcNAc...) (Potential).
FT DISULFID 123 200 Potential.
SQ SEQUENCE 355 AA; 39696 MW; 9B7B6B8F361BCDA2 CRC64;
MAAHADEPVF AARRYNEETT RESAFVYTNA NNTRDPFEGP NYHIAPRWVY NLASLWMIIV
VIASIFTNSL VIVATAKFKK LRHPLNWILV NLAIADLGET VLASTISVFN QVFGYFVLGH
PMCIFEGWTV SVCGITALWS LTIISWERWV VVCKPFGNVK FDGKWAAGGI IFAWTWAIIW
CTPPIFGWSR YWPHGLKTSC GPDVFSGSED PGVASYMVTL LLTCCILPLS VIIICYIFVW
NAIHQVAQQQ KDSESTQKAE KEVSRMVVVM ILAFILCWGP YASFATFSAL NPGYAWHPLA
AALPAYFAKS ATIYNPIIYV FMNRQFRSCI MQLFGKKVED ASEVSGSTTE VSTAS
//
