ID YFEA_ECOLI Reviewed; 729 AA.
AC P23842; P76529; P76954;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 2.
DT 01-MAY-2013, entry version 110.
DE RecName: Full=Uncharacterized protein YfeA;
GN Name=yfeA; OrderedLocusNames=b2395, JW5391;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K.,
RA Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N.,
RA Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H.,
RA Oshima T., Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S.,
RA Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C.,
RA Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-
RT K12 genome corresponding to 50.0-68.8 min on the linkage map and
RT analysis of its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA Mau B., Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1474(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains
RT MG1655 and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-153.
RC STRAIN=K12;
RX PubMed=2201776; DOI=10.1016/0022-2836(90)90339-N;
RA Brun Y.V., Breton R., Lanouette P., Lapointe J.;
RT "Precise mapping and comparison of two evolutionarily related regions
RT of the Escherichia coli K-12 chromosome. Evolution of valU and lysT
RT from an ancestral tRNA operon.";
RL J. Mol. Biol. 214:825-843(1990).
RN [5]
RP INDUCTION, AND RPOS-REPRESSION.
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=19332833; DOI=10.1099/mic.0.024257-0;
RA Sommerfeldt N., Possling A., Becker G., Pesavento C., Tschowri N.,
RA Hengge R.;
RT "Gene expression patterns and differential input into curli fimbriae
RT regulation of all GGDEF/EAL domain proteins in Escherichia coli.";
RL Microbiology 155:1318-1331(2009).
CC -!- INDUCTION: Expressed during exponential and post-exponential
CC growth at both 28 and 37 degrees Celsius. Repressed by RpoS.
CC -!- SIMILARITY: Contains 1 EAL domain.
CC -!- SIMILARITY: Contains 1 GGDEF domain.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA65719.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
CC Sequence=AAA65719.1; Type=Frameshift; Positions=112;
CC Sequence=CAA45395.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
CC Sequence=CAA45395.1; Type=Frameshift; Positions=112;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; U00096; AAC75454.2; -; Genomic_DNA.
DR EMBL; AP009048; BAA16267.2; -; Genomic_DNA.
DR EMBL; M13687; AAA65719.1; ALT_SEQ; Genomic_DNA.
DR EMBL; X63976; CAA45395.1; ALT_SEQ; Genomic_DNA.
DR PIR; H65013; H65013.
DR PIR; S11411; S11411.
DR RefSeq; NP_416896.4; NC_000913.2.
DR RefSeq; YP_490636.1; NC_007779.1.
DR ProteinModelPortal; P23842; -.
DR SMR; P23842; 498-726.
DR DIP; DIP-12011N; -.
DR IntAct; P23842; 1.
DR MINT; MINT-1223642; -.
DR STRING; 511145.b2395; -.
DR EnsemblBacteria; AAC75454; AAC75454; b2395.
DR EnsemblBacteria; BAA16267; BAA16267; BAA16267.
DR GeneID; 12930192; -.
DR GeneID; 946864; -.
DR KEGG; ecj:Y75_p2361; -.
DR KEGG; eco:b2395; -.
DR PATRIC; 32120167; VBIEscCol129921_2492.
DR EchoBASE; EB1135; -.
DR EcoGene; EG11145; yfeA.
DR eggNOG; COG2199; -.
DR HOGENOM; HOG000122953; -.
DR OMA; AQFNLSV; -.
DR ProtClustDB; CLSK880383; -.
DR BioCyc; EcoCyc:EG11145-MONOMER; -.
DR BioCyc; ECOL316407:JW5391-MONOMER; -.
DR Genevestigator; P23842; -.
DR GO; GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 3.20.20.450; -; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR001633; Diguanylate_PEstase_EAL_dom.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR007895; MASE1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF05231; MASE1; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; A/G_cyclase; 1.
DR SUPFAM; SSF141868; SSF141868; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Reference proteome.
FT CHAIN 1 729 Uncharacterized protein YfeA.
FT /FTId=PRO_0000169216.
FT DOMAIN 348 476 GGDEF.
FT DOMAIN 488 729 EAL.
SQ SEQUENCE 729 AA; 83524 MW; F1CF1AA15D592650 CRC64;
MFVEHNLIKN IKIFTLAFTL TVVLIQLSRF ISPLAIIHSS YIFLAWMPLC VMLSILFIFG
WRGVVPVLCG MFCTNLWNFH LSFLQTAVML GSQTFVVLCA CAILRWQLGT RWRYGLTSRY
VWQRLFWLGL VTPIGIKCSM YLVGSFFDFP LKISTFFGDA DAIFTVVDLL SLFTAVLIYN
MLFYYLTRMI VSPHFAQILW RRDIAPSLGK EKRAFTLSWL AALSVLLLLL CTPYENDFIA
GYLVPVFFII FTLGVGKLRY PFLNLTWAVS TLCLLNYNQN FLQGVETEYS LAFILAVLIS
FSVCLLYMVR IYHRSEWLNR RWHLQALTDP LTLLPNFRAL EQAPEQEAGK SFCCLRIDNL
EFMSRHYGLM MRVHCIRSIC RTLLPLMQEN EKLYQLPGSE LLLVLSGPET EGRLQHMVNI
LNSRQIHWNN TGLDMGYGAA WGRFDGNQET LQPLLGQLSW LAEQSCAHHH VLALDSREEM
VSGQTTKQVL LLNTIRTALD QGDLLLYAQP IRNKEGEGYD EILARLKYDG GIMTPDKFLP
LIAQFNLSAR FDLQVLESLL KWLATHPCDK KGPRFSVNLM PLTLLQKNIA GRIIRLFKRY
HISPQAVILE ITEEQAFSNA ESSMYNIEQL HKFGFRIAID DFGTGYANYE RLKRLQADII
KIDGVFVKDI VTNTLDAMIV RSITDLAKAK SLSVVAEFVE TQQQQALLHK LGVQYLQGYL
IGRPQPLAD
//
