ID OPSV_CHICK Reviewed; 347 AA.
AC P28684;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 29-MAY-2013, entry version 80.
DE RecName: Full=Violet-sensitive opsin;
DE AltName: Full=Violet cone opsin;
DE AltName: Full=Violet cone photoreceptor pigment;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;
OC Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Retina;
RX PubMed=1385866; DOI=10.1073/pnas.89.13.5932;
RA Okano T., Kojima D., Fukada Y., Shichida Y., Yoshizawa T.;
RT "Primary structures of chicken cone visual pigments: vertebrate
RT rhodopsins have evolved out of cone visual pigments.";
RL Proc. Natl. Acad. Sci. U.S.A. 89:5932-5936(1992).
CC -!- FUNCTION: Visual pigments are the light-absorbing molecules that
CC mediate vision. They consist of an apoprotein, opsin, covalently
CC linked to cis-retinal.
CC -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC Absorption:
CC Abs(max)=415 nm;
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: The color pigments are found in the cone
CC photoreceptor cells.
CC -!- PTM: Phosphorylated on some or all of the serine and threonine
CC residues present in the C-terminal region.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC Opsin subfamily.
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DR EMBL; M92039; AAA49141.1; -; mRNA.
DR IPI; IPI00589704; -.
DR PIR; C46137; C46137.
DR RefSeq; NP_990769.1; NM_205438.1.
DR UniGene; Gga.814; -.
DR ProteinModelPortal; P28684; -.
DR GeneID; 396419; -.
DR KEGG; gga:396419; -.
DR HOVERGEN; HBG107442; -.
DR KO; K04252; -.
DR NextBio; 20816460; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001760; Opsin.
DR InterPro; IPR001521; Opsin_blue.
DR InterPro; IPR027430; Retinal_BS.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00238; OPSIN.
DR PRINTS; PR00574; OPSINBLUE.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS00238; OPSIN; 1.
PE 1: Evidence at protein level;
KW Chromophore; Complete proteome; Disulfide bond;
KW G-protein coupled receptor; Glycoprotein; Membrane; Phosphoprotein;
KW Photoreceptor protein; Receptor; Reference proteome; Retinal protein;
KW Sensory transduction; Transducer; Transmembrane; Transmembrane helix;
KW Vision.
FT CHAIN 1 347 Violet-sensitive opsin.
FT /FTId=PRO_0000197768.
FT TOPO_DOM 1 31 Extracellular.
FT TRANSMEM 32 56 Helical; Name=1; (Potential).
FT TOPO_DOM 57 68 Cytoplasmic.
FT TRANSMEM 69 94 Helical; Name=2; (Potential).
FT TOPO_DOM 95 108 Extracellular.
FT TRANSMEM 109 128 Helical; Name=3; (Potential).
FT TOPO_DOM 129 147 Cytoplasmic.
FT TRANSMEM 148 171 Helical; Name=4; (Potential).
FT TOPO_DOM 172 197 Extracellular.
FT TRANSMEM 198 225 Helical; Name=5; (Potential).
FT TOPO_DOM 226 247 Cytoplasmic.
FT TRANSMEM 248 271 Helical; Name=6; (Potential).
FT TOPO_DOM 272 279 Extracellular.
FT TRANSMEM 280 304 Helical; Name=7; (Potential).
FT TOPO_DOM 305 347 Cytoplasmic.
FT MOD_RES 291 291 N6-(retinylidene)lysine (By similarity).
FT CARBOHYD 12 12 N-linked (GlcNAc...) (Probable).
FT DISULFID 105 182 Potential.
SQ SEQUENCE 347 AA; 38720 MW; 11B99472DFACE453 CRC64;
MSSDDDFYLF TNGSVPGPWD GPQYHIAPPW AFYLQTAFMG IVFAVGTPLN AVVLWVTVRY
KRLRQPLNYI LVNISASGFV SCVLSVFVVF VASARGYFVF GKRVCELEAF VGTHGGLVTG
WSLAFLAFER YIVICKPFGN FRFSSRHALL VVVATWLIGV GVGLPPFFGW SRYMPEGLQC
SCGPDWYTVG TKYRSEYYTW FLFIFCFIVP LSLIIFSYSQ LLSALRAVAA QQQESATTQK
AEREVSRMVV VMVGSFCLCY VPYAALAMYM VNNRDHGLDL RLVTIPAFFS KSACVYNPII
YCFMNKQFRA CIMETVCGKP LTDDSDASTS AQRTEVSSVS SSQVGPT
//
