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Database: UniProt
Entry: P51034
LinkDB: P51034
Original site: P51034 
ID   CISY_BARQU              Reviewed;         438 AA.
AC   P51034; Q6FZN8;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 3.
DT   11-JUN-2014, entry version 84.
DE   RecName: Full=Citrate synthase;
DE            EC=2.3.3.16;
GN   Name=gltA; OrderedLocusNames=BQ06850;
OS   Bartonella quintana (strain Toulouse) (Rochalimaea quintana).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bartonellaceae; Bartonella.
OX   NCBI_TaxID=283165;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Toulouse;
RX   PubMed=15210978; DOI=10.1073/pnas.0305659101;
RA   Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H.,
RA   Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M.,
RA   La Scola B., Holmberg M., Andersson S.G.E.;
RT   "The louse-borne human pathogen Bartonella quintana is a genomic
RT   derivative of the zoonotic agent Bartonella henselae.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 60-379.
RC   STRAIN=ATCC VR-358 / Fuller / CIP 107027;
RX   PubMed=8863415;
RA   Birtles R.J., Raoult D.;
RT   "Comparison of partial citrate synthase gene (gltA) sequences for
RT   phylogenetic analysis of Bartonella species.";
RL   Int. J. Syst. Bacteriol. 46:891-897(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 268-379.
RC   STRAIN=ATCC VR-358 / Fuller / CIP 107027;
RA   Jones D.C., Regnery R., Bowen M.;
RT   "Bartonella species characterization: citrate synthase (gltA) PCR
RT   product sequence analysis.";
RL   Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + H(2)O + oxaloacetate = citrate +
CC       CoA.
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       isocitrate from oxaloacetate: step 1/2.
CC   -!- MISCELLANEOUS: Citrate synthase is found in nearly all cells
CC       capable of oxidative metabolism.
CC   -!- SIMILARITY: Belongs to the citrate synthase family.
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DR   EMBL; BX897700; CAF26174.1; -; Genomic_DNA.
DR   EMBL; Z70014; CAA93836.1; -; Genomic_DNA.
DR   EMBL; U28073; AAA74978.1; -; Genomic_DNA.
DR   RefSeq; YP_032322.1; NC_005955.1.
DR   ProteinModelPortal; P51034; -.
DR   SMR; P51034; 2-429.
DR   STRING; 283165.BQ06850; -.
DR   PRIDE; P51034; -.
DR   EnsemblBacteria; CAF26174; CAF26174; BQ06850.
DR   GeneID; 2867054; -.
DR   KEGG; bqu:BQ06850; -.
DR   PATRIC; 31952667; VBIBarQui58630_0759.
DR   eggNOG; COG0372; -.
DR   HOGENOM; HOG000021224; -.
DR   KO; K01647; -.
DR   OMA; KETCDEV; -.
DR   OrthoDB; EOG6P8TP4; -.
DR   BioCyc; BQUI283165:GHZA-684-MONOMER; -.
DR   UniPathway; UPA00223; UER00717.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.230.10; -; 1.
DR   Gene3D; 1.10.580.10; -; 1.
DR   InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR   InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR   InterPro; IPR002020; Citrate_synthase-like.
DR   InterPro; IPR016141; Citrate_synthase-like_core.
DR   InterPro; IPR019810; Citrate_synthase_AS.
DR   InterPro; IPR024176; Citrate_synthase_bac-typ.
DR   InterPro; IPR010953; Citrate_synthase_typ-II.
DR   PANTHER; PTHR11739; PTHR11739; 1.
DR   Pfam; PF00285; Citrate_synt; 1.
DR   PIRSF; PIRSF001369; Citrate_synth; 1.
DR   PRINTS; PR00143; CITRTSNTHASE.
DR   SUPFAM; SSF48256; SSF48256; 1.
DR   TIGRFAMs; TIGR01798; cit_synth_I; 1.
DR   PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Transferase; Tricarboxylic acid cycle.
FT   CHAIN         1    438       Citrate synthase.
FT                                /FTId=PRO_0000169935.
FT   ACT_SITE    306    306       By similarity.
FT   ACT_SITE    364    364       By similarity.
FT   CONFLICT    117    117       Q -> R (in Ref. 2; CAA93836).
FT   CONFLICT    224    224       F -> C (in Ref. 2; CAA93836).
SQ   SEQUENCE   438 AA;  49464 MW;  98ED2C4A41ACD5E4 CRC64;
     MSENKAHITV NNKKIELSVR KGTLGPGVIE IASLYKETDT FTYDPGFTST ASCESKITYI
     DGDKGILLYC GYPIDQLAEK GDFLESCYLL LYGELPTKQE KIDFDRCIMQ HMMVHEQFTR
     FFHGFRRDSH PMAVMVACLG AMSAFYHDSI DIKDAQQRMI AAIRLISKVP TLAAMAYKYS
     IGQAFVYPRN DLSYAANFLH MCFSVPCEEY KINPVLSRAM DRIFTLHADH EQNASTSTVR
     LVGSSGANPF ACIAAGVACL WGPAHGGANE ACLKMLQKIG SVERIPEFIA RAKDKNDPFR
     LMGFGHRVYK NYDPRAKIMQ QTCHEVLKEL NIQDDPLLDI AIALENTALN DEYFIEKKLY
     PNVDFYSGIT LKALGFPTEM FTVLFALARS IGWVAQWKEM IEDPAQKIGR PRQLYTGYAA
     REYVSIDKRI SKNKMTTQ
//
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