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Database: UniProt
Entry: P51185
LinkDB: P51185
Original site: P51185 
ID   PTSO_KLEOX              Reviewed;          90 AA.
AC   P51185;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   01-OCT-2014, entry version 78.
DE   RecName: Full=Phosphocarrier protein NPr;
DE            EC=2.7.11.-;
DE   AltName: Full=Nitrogen-related HPr;
GN   Name=ptsO; Synonyms=npr;
OS   Klebsiella oxytoca.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=571;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=M5a1;
RA   Merrick M.J., Taylor M.;
RT   "Sequence and characterisation of distal genes in the Klebsiella
RT   pneumoniae rpoN operon.";
RL   Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the phosphoenolpyruvate-dependent nitrogen-
CC       metabolic phosphotransferase system (nitrogen-metabolic PTS), that
CC       seems to be involved in regulating nitrogen metabolism. The
CC       phosphoryl group from phosphoenolpyruvate (PEP) is transferred to
CC       the phosphoryl carrier protein NPr by enzyme I-Ntr. Phospho-NPr
CC       then transfers it to EIIA-Ntr. Could function in the
CC       transcriptional regulation of sigma-54 dependent operons in
CC       conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY: Protein NPr N(pi)-phospho-L-histidine +
CC       protein EIIA-Ntr = protein NPr + protein EIIA-Ntr N(tau)-phospho-
CC       L-histidine.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HPr family. {ECO:0000305}.
CC   -!- SIMILARITY: Contains 1 HPr domain. {ECO:0000255|PROSITE-
CC       ProRule:PRU00681}.
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DR   EMBL; Z50803; CAA90685.1; -; Genomic_DNA.
DR   PIR; S60667; S60667.
DR   ProteinModelPortal; P51185; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1340.10; -; 1.
DR   InterPro; IPR000032; HPr_prot-like.
DR   InterPro; IPR001020; PTS_HPr_His_P_site.
DR   InterPro; IPR002114; PTS_HPr_Ser_P_site.
DR   Pfam; PF00381; PTS-HPr; 1.
DR   PRINTS; PR00107; PHOSPHOCPHPR.
DR   SUPFAM; SSF55594; SSF55594; 1.
DR   TIGRFAMs; TIGR01003; PTS_HPr_family; 1.
DR   PROSITE; PS51350; PTS_HPR_DOM; 1.
DR   PROSITE; PS00369; PTS_HPR_HIS; 1.
DR   PROSITE; PS00589; PTS_HPR_SER; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Kinase; Phosphotransferase system;
KW   Serine/threonine-protein kinase; Transferase.
FT   CHAIN         1     90       Phosphocarrier protein NPr.
FT                                /FTId=PRO_0000107893.
FT   DOMAIN        2     90       HPr. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00681}.
FT   ACT_SITE     16     16       Pros-phosphohistidine intermediate.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00681}.
SQ   SEQUENCE   90 AA;  9820 MW;  D5DBD7514B1149C6 CRC64;
     MTVKQTVEIS NKLGMHARPA MKLFELMQNY DAEVLLRNDE GTVAEANSVI ALLMLDSAKG
     RQIEIEANGP QEVEALAAVI ALFNAGFDED
//
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