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Database: UniProt
Entry: P58480
LinkDB: P58480
Original site: P58480 
ID   HTPG_SALTY              Reviewed;         624 AA.
AC   P58480;
DT   13-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   13-DEC-2001, sequence version 1.
DT   29-OCT-2014, entry version 88.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505};
GN   OrderedLocusNames=STM0487;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA   Waterston R., Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT   LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL19441.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE006468; AAL19441.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_459482.2; NC_003197.1.
DR   ProteinModelPortal; P58480; -.
DR   SMR; P58480; 1-624.
DR   STRING; 99287.STM0487.S; -.
DR   PRIDE; P58480; -.
DR   EnsemblBacteria; AAL19441; AAL19441; STM0487.
DR   GeneID; 1252007; -.
DR   KEGG; stm:STM0487.S; -.
DR   PATRIC; 32379317; VBISalEnt20916_0520.
DR   KO; K04079; -.
DR   OMA; MSHLTEF; -.
DR   OrthoDB; EOG65TRNM; -.
DR   PhylomeDB; P58480; -.
DR   BioCyc; SENT99287:GCTI-490-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR019805; Heat_shock_protein_90_CS.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS00298; HSP90; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Complete proteome; Cytoplasm;
KW   Nucleotide-binding; Reference proteome; Stress response.
FT   CHAIN         1    624       Chaperone protein HtpG.
FT                                /FTId=PRO_0000063013.
FT   REGION        1    336       A; substrate-binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_00505}.
FT   REGION      337    552       B. {ECO:0000255|HAMAP-Rule:MF_00505}.
FT   REGION      553    624       C. {ECO:0000255|HAMAP-Rule:MF_00505}.
SQ   SEQUENCE   624 AA;  71487 MW;  0974B2B1B38D0B39 CRC64;
     MKGQETRGFQ SEVKQLLHLM IHSLYSNKEI FLRELISNAS DAADKLRFRA LSNPDLYEGD
     GELRVRVSFD KDKRTLTIAD NGVGMNRDEV IDHLGTIAKS GTKSFLESMG SDQAKDSQLI
     GQFGVGFYSA FIVADKVTVR TRAAGDKPEN GVFWESAGEG EYTVADITKN DRGTEITLHL
     REGEDEFLDD WRVRSIISKY SDHIALPVEI EKREEKDGET VISWEKINKA QALWTRNKSE
     IKDDEYNEFY KHIAHDFTDP LTWSHNRVEG KQEYTSLLYI PSQAPWDLWN RDHKHGLKLY
     VQRVFIMDDA EQFMPNYLRF VRGLIDSNDL PLNVSREILQ DSTVTRNLRS ALTKRVLQML
     EKLAKDDAEK YQTFWKQFGL VLKEGPAEDH ANQEAIAKLL RFASTHTDSS AQTVSLEDYV
     SRMKEGQEKI YYITADSYAA AKNSPHLELL RKKGIEVLLL SDRIDEWMMN YLTEFDGKAF
     QSVAKADESI EKLADEVDEN AKEAEKALEP FVERVKTLLG DRVKDVRLTH RLTDTPAIVT
     TDADEMSTQM AKLFAAAGQS VPEVKYIFEL NPDHVLVKRT ADTKDEAQFK EWVELLLDQA
     LFAERGTLED PNQFIRRMNQ LLVS
//
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