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Database: UniProt
Entry: P71359
LinkDB: P71359
Original site: P71359 
ID   RECQ_HAEIN              Reviewed;         619 AA.
AC   P71359;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   19-FEB-2014, entry version 94.
DE   RecName: Full=ATP-dependent DNA helicase RecQ;
DE            EC=3.6.4.12;
GN   Name=recQ; OrderedLocusNames=HI_0728;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M.,
RA   Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D.,
RA   Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C.,
RA   Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M.,
RA   Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O.,
RA   Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   SEQUENCE REVISION.
RA   White O., Clayton R.A., Kerlavage A.R., Fleischmann R.D.;
RL   Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA helicase (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC   -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC   -!- SIMILARITY: Contains 1 helicase ATP-binding domain.
CC   -!- SIMILARITY: Contains 1 helicase C-terminal domain.
CC   -!- SIMILARITY: Contains 1 HRDC domain.
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DR   EMBL; L42023; AAC22387.1; -; Genomic_DNA.
DR   RefSeq; NP_438887.1; NC_000907.1.
DR   ProteinModelPortal; P71359; -.
DR   SMR; P71359; 16-519, 536-608.
DR   STRING; 71421.HI0728; -.
DR   EnsemblBacteria; AAC22387; AAC22387; HI_0728.
DR   GeneID; 949757; -.
DR   KEGG; hin:HI0728; -.
DR   PATRIC; 20190093; VBIHaeInf48452_0762.
DR   eggNOG; COG0514; -.
DR   KO; K03654; -.
DR   OMA; YCLSRAK; -.
DR   OrthoDB; EOG6ZSPDC; -.
DR   ProtClustDB; CLSK870478; -.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006200; P:ATP catabolic process; IEA:GOC.
DR   GO; GO:0032508; P:DNA duplex unwinding; IEA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.80; -; 1.
DR   InterPro; IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
DR   InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR   InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR010997; HRDC-like.
DR   InterPro; IPR002121; HRDC_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR018982; RQC_domain.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00570; HRDC; 1.
DR   Pfam; PF09382; RQC; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00341; HRDC; 1.
DR   SMART; SM00956; RQC; 1.
DR   SUPFAM; SSF47819; SSF47819; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR01389; recQ; 1.
DR   TIGRFAMs; TIGR00614; recQ_fam; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50967; HRDC; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; DNA-binding; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN         1    619       ATP-dependent DNA helicase RecQ.
FT                                /FTId=PRO_0000205036.
FT   DOMAIN       37    205       Helicase ATP-binding.
FT   DOMAIN      229    374       Helicase C-terminal.
FT   DOMAIN      535    615       HRDC.
FT   NP_BIND      50     57       ATP (Potential).
FT   MOTIF       149    152       DEAH box.
SQ   SEQUENCE   619 AA;  70056 MW;  4785BD6E599337BB CRC64;
     MLDSPLLSKI IEKPTALSVL KSVFGYQSFR KGQEEVINAA LNGQDALVVM ATGNGKSLCY
     QIPALCFDGL TLVISPLISL MKDQVDQLQA NGIEADFLNS SQTLEQQQQV QNKLISGQLK
     LLYVSPEKVM TNSFFQLISY SKVCFIAIDE AHCISQWGHD FRPEYTQLGG LKASFPDAPI
     MALTATADYA TQQDILRHLN LKNLHKYIGS FDRPNIRYTL EEKYKPMEQL TRFVLAQKGK
     SGIIYCNSRN KVERIAESLR NKGVSAAAYH AGMETAIRER VQQDFQRDNV QVVVATIAFG
     MGINKSNVRF VAHFDLPRSI ESYYQETGRA GRDDLPAEAV LFYEPADYAW LQKILLEKPE
     TPQRQIEQHK LEAIGEFAES QTCRRLVLLN YFGEHRQTPC NNCDICLDPP KKYDGLVDAQ
     KVMSTIYRVG QCFGAHYVIA VLRGMHNQKI IERQHHKLSV YGIGKDKSKE HWQSVIRQLI
     HLGFVQQVIS ELNPTLQLTE SAKVILKGEE PLELAMPRIS AISKIAHNPQ RQGVANYDKD
     LFARLRFLRK QIADKENIPP YIVFNDATLQ EMAQYMPTSN IEMLQINGVG SIKLERFGQP
     FMALIQEHKA ILANAQNND
//
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