ID RECQ_HAEIN Reviewed; 619 AA.
AC P71359;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 01-MAY-2013, entry version 90.
DE RecName: Full=ATP-dependent DNA helicase RecQ;
DE EC=3.6.4.12;
GN Name=recQ; OrderedLocusNames=HI_0728;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M.,
RA Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D.,
RA Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C.,
RA Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M.,
RA Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O.,
RA Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
RN [2]
RP SEQUENCE REVISION.
RA White O., Clayton R.A., Kerlavage A.R., Fleischmann R.D.;
RL Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA helicase (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC -!- SIMILARITY: Contains 1 helicase ATP-binding domain.
CC -!- SIMILARITY: Contains 1 helicase C-terminal domain.
CC -!- SIMILARITY: Contains 1 HRDC domain.
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DR EMBL; L42023; AAC22387.1; -; Genomic_DNA.
DR RefSeq; NP_438887.1; NC_000907.1.
DR ProteinModelPortal; P71359; -.
DR SMR; P71359; 16-519, 536-608.
DR STRING; 71421.HI0728; -.
DR EnsemblBacteria; AAC22387; AAC22387; HI_0728.
DR GeneID; 949757; -.
DR KEGG; hin:HI0728; -.
DR PATRIC; 20190093; VBIHaeInf48452_0762.
DR eggNOG; COG0514; -.
DR KO; K03654; -.
DR OMA; YCLSRAK; -.
DR ProtClustDB; CLSK870478; -.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 1.10.150.80; -; 1.
DR InterPro; IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR011991; WHTH_DNA-bd_dom.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC_like; 1.
DR TIGRFAMs; TIGR01389; recQ; 1.
DR TIGRFAMs; TIGR00614; recQ_fam; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; FALSE_NEG.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; DNA-binding; Helicase; Hydrolase;
KW Nucleotide-binding; Reference proteome.
FT CHAIN 1 619 ATP-dependent DNA helicase RecQ.
FT /FTId=PRO_0000205036.
FT DOMAIN 37 205 Helicase ATP-binding.
FT DOMAIN 229 374 Helicase C-terminal.
FT DOMAIN 535 615 HRDC.
FT NP_BIND 50 57 ATP (Potential).
FT MOTIF 149 152 DEAH box.
SQ SEQUENCE 619 AA; 70056 MW; 4785BD6E599337BB CRC64;
MLDSPLLSKI IEKPTALSVL KSVFGYQSFR KGQEEVINAA LNGQDALVVM ATGNGKSLCY
QIPALCFDGL TLVISPLISL MKDQVDQLQA NGIEADFLNS SQTLEQQQQV QNKLISGQLK
LLYVSPEKVM TNSFFQLISY SKVCFIAIDE AHCISQWGHD FRPEYTQLGG LKASFPDAPI
MALTATADYA TQQDILRHLN LKNLHKYIGS FDRPNIRYTL EEKYKPMEQL TRFVLAQKGK
SGIIYCNSRN KVERIAESLR NKGVSAAAYH AGMETAIRER VQQDFQRDNV QVVVATIAFG
MGINKSNVRF VAHFDLPRSI ESYYQETGRA GRDDLPAEAV LFYEPADYAW LQKILLEKPE
TPQRQIEQHK LEAIGEFAES QTCRRLVLLN YFGEHRQTPC NNCDICLDPP KKYDGLVDAQ
KVMSTIYRVG QCFGAHYVIA VLRGMHNQKI IERQHHKLSV YGIGKDKSKE HWQSVIRQLI
HLGFVQQVIS ELNPTLQLTE SAKVILKGEE PLELAMPRIS AISKIAHNPQ RQGVANYDKD
LFARLRFLRK QIADKENIPP YIVFNDATLQ EMAQYMPTSN IEMLQINGVG SIKLERFGQP
FMALIQEHKA ILANAQNND
//
