ID P93204_SOLLC Unreviewed; 766 AA.
AC P93204;
DT 01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1997, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=SBT1 protein {ECO:0000313|EMBL:CAA67429.1};
DE SubName: Full=Subtilisin-like protease {ECO:0000313|EMBL:CAA06999.1};
GN Name=SBT1 {ECO:0000313|EMBL:CAA67429.1};
GN Synonyms=sbt1 {ECO:0000313|EMBL:CAA06999.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EMBL:CAA67429.1};
RN [1] {ECO:0000313|EMBL:CAA06999.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10350089; DOI=10.1023/A:1006193414434;
RA Meichtry J., Amrhein N., Schaller A.;
RT "Characterization of the subtilase gene family in tomato (Lycopersicon
RT esculentum Mill.).";
RL Plant Mol. Biol. 39:749-760(1999).
RN [2] {ECO:0000313|EMBL:CAA67429.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10671566; DOI=10.1074/jbc.275.7.5193;
RA Janzik I., Macheroux P., Amrhein N., Schaller A.;
RT "LeSBT1, a subtilase from tomato plants. Overexpression in insect cells,
RT purification, and characterization.";
RL J. Biol. Chem. 275:5193-5199(2000).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; AJ006378; CAA06999.1; -; Genomic_DNA.
DR EMBL; X98929; CAA67429.1; -; mRNA.
DR PIR; T07171; T07171.
DR RefSeq; NP_001234282.2; NM_001247353.3.
DR AlphaFoldDB; P93204; -.
DR MEROPS; S08.112; -.
DR GeneID; 544117; -.
DR KEGG; sly:544117; -.
DR OrthoDB; 11910at2759; -.
DR ExpressionAtlas; P93204; baseline and differential.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF469; SUBTILISIN-LIKE PROTEASE SBT1.7; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..766
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010972370"
FT DOMAIN 30..105
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 131..586
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 370..456
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 657..762
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 139
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 212
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 542
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 766 AA; 81355 MW; 5D7ACC5DCEFFE8E7 CRC64;
MERLRLMFLL ILMVVLFHVF VDARQNQKKT YIIHMDKFNM PADFDDHTQW YDSSLKSVSK
SANMLYTYNS VIHGYSTQLT ADEAKALAQQ PGILLVHEEV IYELHTTRSP TFLGLEGRES
RSFFPQTEAR SEVIIGVLDT GVWPESKSFD DTGLGQVPAS WKGKCQTGKN FDASSCNRKL
IGARFFSQGY EAAFGAIDET IESKSPRDDE GHGTHTATTA AGSVVTGASL LGYATGTARG
MASHARVAAY KVCWTGGCFS SDILAGMDQA VIDGVNVLSL SLGGTISDYH RDIVAIGAFS
AASQGIFVSC SAGNGGPSSG TLSNVAPWIT TVGAGTMDRE FPAYIGIGNG KKLNGVSLYS
GKALPSSVMP LVYAGNVSQS SNGNLCTSGS LIPEKVAGKI VVCDRGMNAR AQKGLVVKDA
GGIGMILANT DTYGDELVAD AHLIPTAAVG QTAGNLIKQY IASNSNPTAT IAFGGTKLGV
QPSPVVAAFS SRGPNPITPD VLKPDLIAPG VNILAGWTGK VGPTGLQEDT RNVGFNIISG
TSMSCPHVSG LAALLKAAHP EWSPAAIRSA LMTTSYSTYK NGKTIEDVAT GMSSTPFDYG
AGHVNPTAAV SPGLVYDLTV DDYINFLCAL DYSPSMIKVI AKRDISCDEN KEYRVADLNY
PSFSIPMETA WGEHADSSTP TVTRYTRTLT NVGNPATYKA SVSSETQDVK ILVEPQTLTF
SRKNEKKTYT VTFTATSKPS GTTSFARLEW SDGQHVVASP IAFSWT
//
