ID P96310_CALBS Unreviewed; 341 AA.
AC P96310;
DT 01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1997, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=cellulase {ECO:0000256|ARBA:ARBA00012601};
DE EC=3.2.1.4 {ECO:0000256|ARBA:ARBA00012601};
DE Flags: Fragment;
GN Name=celB {ECO:0000313|EMBL:CAB06784.1};
OS Caldicellulosiruptor bescii (Anaerocellum thermophilum).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=31899 {ECO:0000313|EMBL:CAB06784.1};
RN [1] {ECO:0000313|EMBL:CAB06784.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Z-1320 {ECO:0000313|EMBL:CAB06784.1};
RA Zverlov V.;
RL Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000966};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|RuleBase:RU361153}.
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DR EMBL; Z86104; CAB06784.1; -; Genomic_DNA.
DR AlphaFoldDB; P96310; -.
DR CAZy; CBM3; Carbohydrate-Binding Module Family 3.
DR CAZy; GH5; Glycoside Hydrolase Family 5.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR018087; Glyco_hydro_5_CS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR35923:SF2; CELLULASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR35923; MAJOR EXTRACELLULAR ENDOGLUCANASE; 1.
DR Pfam; PF00150; Cellulase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023326};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361153};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326}.
FT DOMAIN 9..273
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAB06784.1"
SQ SEQUENCE 341 AA; 39765 MW; 0E978802DD6AD007 CRC64;
GIYPKPNINY YVNPELEGKN SLEVFDIVVQ ICKEVGLKIM LDIHSIKTDA MGHIYPVWYG
LDKFTPEDFY KACEWITNRY KNDDTIIAFD LKNEPHGKPW QDTTFAKWDN STDINNWKYA
AETCAKRILN INPNLLIVIE GIEAYPKDDV TWTSKSYSDY YSTWWGGNLR GVKKYPINLG
KYQNKVVYSP HDYGPSVYQQ PWFYPGFTKE SLLQDCWRPN WAYIMEENIA PLLIGEWGGY
LDGADNEKWM RYLRDYIIEN HIHHTFWCFN ANSGDTGGMV GYDFTTWDEK KYSFLKPALW
QDSQGRFVGL DHKRPLGTNG KNINITIYYN NNEPAPVPAA K
//
