ID DNJB9_RAT Reviewed; 222 AA.
AC P97554;
DT 18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 2.
DT 01-MAY-2013, entry version 86.
DE RecName: Full=DnaJ homolog subfamily B member 9;
DE AltName: Full=Microvascular endothelial differentiation gene 1 protein;
DE Short=Mdg-1;
GN Name=Dnajb9; Synonyms=Mdg1;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Epididymis;
RX PubMed=11525638; DOI=10.1006/excr.2001.5294;
RA Proels F., Mayer M.P., Renner O., Czarnecki P.G., Ast M., Gaessler C.,
RA Wilting J., Kurz H., Christ B.;
RT "Upregulation of the cochaperone mdg1 in endothelial cells is induced
RT by stress and during in vitro angiogenesis.";
RL Exp. Cell Res. 269:42-53(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Heart;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Acts as a co-chaperone with an Hsp70 protein.
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Stress induces its
CC translocation to the nucleus.
CC -!- SIMILARITY: Contains 1 J domain.
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DR EMBL; X98993; CAA67434.2; -; mRNA.
DR EMBL; BC070915; AAH70915.1; -; mRNA.
DR IPI; IPI00205524; -.
DR RefSeq; NP_036831.2; NM_012699.2.
DR UniGene; Rn.29778; -.
DR ProteinModelPortal; P97554; -.
DR SMR; P97554; 27-105.
DR STRING; 10116.ENSRNOP00000005363; -.
DR Ensembl; ENSRNOT00000005363; ENSRNOP00000005363; ENSRNOG00000004006.
DR GeneID; 24908; -.
DR KEGG; rno:24908; -.
DR UCSC; RGD:3070; rat.
DR CTD; 4189; -.
DR RGD; 3070; Dnajb9.
DR eggNOG; COG0484; -.
DR GeneTree; ENSGT00700000104316; -.
DR HOGENOM; HOG000290187; -.
DR HOVERGEN; HBG051372; -.
DR InParanoid; P97554; -.
DR KO; K09515; -.
DR OMA; GLFDDMF; -.
DR OrthoDB; EOG4B2SZB; -.
DR NextBio; 604821; -.
DR Genevestigator; P97554; -.
DR GermOnline; ENSRNOG00000004006; Rattus norvegicus.
DR GO; GO:0005783; C:endoplasmic reticulum; TAS:RGD.
DR GO; GO:0005730; C:nucleolus; IDA:UniProtKB.
DR GO; GO:0030433; P:ER-associated protein catabolic process; IEA:Compara.
DR GO; GO:0043066; P:negative regulation of apoptotic process; TAS:RGD.
DR GO; GO:0006950; P:response to stress; TAS:RGD.
DR Gene3D; 1.10.287.110; -; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR Pfam; PF00226; DnaJ; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; DnaJ_N; 1.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 2: Evidence at transcript level;
KW Chaperone; Complete proteome; Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1 222 DnaJ homolog subfamily B member 9.
FT /FTId=PRO_0000071034.
FT DOMAIN 26 90 J.
SQ SEQUENCE 222 AA; 25717 MW; 08BF5347F20B65DC CRC64;
MATPQSVFVF AICILMITEL ILASKNYYDI LGVPKSASER QIKKAFHKLA MKYHPDKNKS
PDAEAKFREI AEAYETLSDA NRRKEYDIIG HSAFTNGKGQ RSNGSPFEQS FNFNFDDLFK
DFNLFGQNQN TRSKKHFENH FQTRQDGSSR QRHHFQEFSF GGGLFDDMFE DMEKMFSFSG
FDSTNRRTVQ TENRFHGSSK HCRTVTQRRG NMVTTYTDCS GQ
//
