ID PSF2_CANGA Reviewed; 215 AA.
AC Q6FS76;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 101.
DE RecName: Full=DNA replication complex GINS protein PSF2;
GN Name=PSF2; OrderedLocusNames=CAGL0H02849g;
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. Has a role in chromosome segregation (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
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DR EMBL; CR380954; CAG59851.1; -; Genomic_DNA.
DR RefSeq; XP_446918.1; XM_446918.1.
DR AlphaFoldDB; Q6FS76; -.
DR SMR; Q6FS76; -.
DR STRING; 284593.Q6FS76; -.
DR EnsemblFungi; CAGL0H02849g-T; CAGL0H02849g-T-p1; CAGL0H02849g.
DR GeneID; 2888574; -.
DR KEGG; cgr:CAGL0H02849g; -.
DR CGD; CAL0131642; CAGL0H02849g.
DR VEuPathDB; FungiDB:B1J91_H02849g; -.
DR VEuPathDB; FungiDB:CAGL0H02849g; -.
DR eggNOG; KOG4071; Eukaryota.
DR HOGENOM; CLU_078274_1_1_1; -.
DR InParanoid; Q6FS76; -.
DR OMA; DSLNCMY; -.
DR Proteomes; UP000002428; Chromosome H.
DR GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR GO; GO:0000811; C:GINS complex; IEA:EnsemblFungi.
DR GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR GO; GO:1902969; P:mitotic DNA replication; IEA:EnsemblFungi.
DR CDD; cd11712; GINS_A_psf2; 1.
DR CDD; cd21694; GINS_B_Psf2; 1.
DR Gene3D; 1.20.58.1020; -; 1.
DR Gene3D; 3.40.5.50; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR PANTHER; PTHR12772:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR Pfam; PF05916; Sld5; 1.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW Chromosome partition; DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..215
FT /note="DNA replication complex GINS protein PSF2"
FT /id="PRO_0000255422"
SQ SEQUENCE 215 AA; 24961 MW; AFBB6EDA6F50D893 CRC64;
MALPAHLQET FSPEEVQFLV EEETVKIFPR ITTRQKRRDK NRGAYGDVDT KWSMLTTEND
NLNNMVAMRS TEVKLWIALL LKQQNKCSIV APSWLTLREL NRKIQQETNN SDRFCDLPWN
WLVIANVLFA KAADDFHDPV HELRSKVQDL REIRQTKVLK GLKQLNASHL QLDNLSLLEI
NELRPFIVRT MDKLREIHDS ANTDGGVVDG DEEEI
//
