ID Q02YN0_LACLS Unreviewed; 461 AA.
AC Q02YN0;
DT 14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 14-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:ABJ72942.1};
GN OrderedLocusNames=LACR_1428 {ECO:0000313|EMBL:ABJ72942.1};
OS Lactococcus lactis subsp. cremoris (strain SK11).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus; Lactococcus cremoris subsp. cremoris.
OX NCBI_TaxID=272622 {ECO:0000313|EMBL:ABJ72942.1, ECO:0000313|Proteomes:UP000000240};
RN [1] {ECO:0000313|EMBL:ABJ72942.1, ECO:0000313|Proteomes:UP000000240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK11 {ECO:0000313|EMBL:ABJ72942.1,
RC ECO:0000313|Proteomes:UP000000240};
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P.,
RA Kozyavkin S., Weimer B., Mills D.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
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DR EMBL; CP000425; ABJ72942.1; -; Genomic_DNA.
DR RefSeq; WP_011676231.1; NC_008527.1.
DR AlphaFoldDB; Q02YN0; -.
DR KEGG; llc:LACR_1428; -.
DR HOGENOM; CLU_047234_0_0_9; -.
DR Proteomes; UP000000240; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR CDD; cd01066; APP_MetAP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF2; XAA-PRO AMINOPEPTIDASE P-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:ABJ72942.1};
KW Hydrolase {ECO:0000313|EMBL:ABJ72942.1};
KW Protease {ECO:0000313|EMBL:ABJ72942.1}.
FT DOMAIN 32..139
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 205..398
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 461 AA; 52325 MW; 58A19D81DCA85F3A CRC64;
MNKEIVYERI NEPKLFNNVP PVTLTDKTLE ERKEKLLSIM AKEQYDALII YADKEHGSNF
EYFTGFIPRF EEGLLIIDKN GKATLVLGNE NLKMSKHSRI GANLIHYPQF SLPNQPMDNE
KNLTQIFKEL KLYKNKKIGL IGWKMFTTQN EEPSELFDLP YFIVDALKNS LSTDTIVTNA
AHLLIGPKGI RTINNANELA HYEYGANLAS RCILNAMNQL KIGMRETEIG ALLSDEGQAH
SVITIAAAGE RFENANFYPT YKKIKFGEAI SMTTGFKGGL SSRTGFLINE ERELPENQKD
YLERVVIPYY KAIVAWLENI SLGMLGGELY EIIDKTLPKA SYHWHLNPGH FVADEEWMSS
SLSKNSQRQI ASGMIFQIDI IPSVAGYTGV SAEKCVAIAD QSLQNELKVK YPELWERITS
RRNYIINELK IDLSPDVLPL SNTVGYLRPF LLEKNKALKV K
//
