ID   Q04901_HALRO            Unreviewed;      1161 AA.
AC   Q04901;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   03-APR-2013, entry version 71.
DE   SubName: Full=Entactin/nidogen;
OS   Halocynthia roretzi (Sea squirt).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Stolidobranchia;
OC   Pyuridae; Halocynthia.
OX   NCBI_TaxID=7729;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Muscle;
RX   PubMed=8477687; DOI=10.1111/j.1432-1033.1993.tb17729.x;
RA   Nakae H., Sugano M., Ishimori Y., Endo T., Obinata T.;
RT   "Ascidian entactin/nidogen: implicaiton of evolution by shuffling two
RT   kinds of cysteine-rich motifs.";
RL   Eur. J. Biochem. 213:11-19(1993).
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DR   EMBL; D14038; BAA03127.1; -; mRNA.
DR   PIR; S31213; S31213.
DR   HSSP; P01130; 1HZ8.
DR   ProteinModelPortal; Q04901; -.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   Gene3D; 2.40.155.10; -; 1.
DR   Gene3D; 4.10.800.10; -; 3.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR000742; EG-like_dom.
DR   InterPro; IPR013032; EGF-like_CS.
DR   InterPro; IPR006605; G2_nidogen/fibulin_G2F.
DR   InterPro; IPR009017; GFP.
DR   InterPro; IPR023413; GFP_like.
DR   InterPro; IPR000033; LDLR_classB_rpt.
DR   InterPro; IPR003886; Nidogen_extracell_dom.
DR   InterPro; IPR000716; Thyroglobulin_1.
DR   Pfam; PF07474; G2F; 1.
DR   Pfam; PF00058; Ldl_recept_b; 2.
DR   Pfam; PF06119; NIDO; 1.
DR   Pfam; PF00086; Thyroglobulin_1; 3.
DR   SMART; SM00181; EGF; 1.
DR   SMART; SM00682; G2F; 1.
DR   SMART; SM00135; LY; 5.
DR   SMART; SM00539; NIDO; 1.
DR   SMART; SM00211; TY; 3.
DR   SUPFAM; SSF54511; GFP_like; 1.
DR   SUPFAM; SSF57610; Thyroglobulin_1; 3.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
DR   PROSITE; PS51120; LDLRB; 4.
DR   PROSITE; PS51220; NIDO; 1.
DR   PROSITE; PS50993; NIDOGEN_G2; 1.
DR   PROSITE; PS00484; THYROGLOBULIN_1_1; 2.
DR   PROSITE; PS51162; THYROGLOBULIN_1_2; 3.
PE   2: Evidence at transcript level;
KW   Disulfide bond; EGF-like domain; Repeat.
SQ   SEQUENCE   1161 AA;  128472 MW;  F952B8DB9A700D30 CRC64;
     MEKVALCMLA VFAVGHSLLV EDFYPFDREN DNLVPKGDSE SSPQQKLSMP IVFYDQKYDS
     VTVHTDGFIT LENVGADTDG EVLLAPFMSD LDTELSGDIF FREHKDNATI ARANTDVREA
     FIETAGDFNA GSVFVVTWDK VQSASREDGV TFTFQCIVAT DGAATFAIFL YPQDGLAVGE
     NAVKGVRNEV TARAGFNDGG REQLEILSAD ELLGGDNAGS QGQWIFQIGG IMFNNDEASK
     ESEKHHVKKT RQSGFQVSEV NFNEDFNIDL EAECGTPCSD FGTCREVGNG FCCVCDEGYF
     GNGQVCIEKD IAVRYNGQVS GYSIVLNHDN SWSNETAGAI DLHGYVVTSE GRAFTVLNGN
     LSPALARSLQ PMTIFGTTLG WLFSKTTQPA INGVQYSGGK VSSHTYIRYT TGAYEFRIDQ
     KYDRVVSDES GVGKVLNGKM TFRGRLPAVG EKDTVTIDDY SQVYTKTGPG IIRTHDTRSY
     TVRNVTHSYT VDQTIKFEGC EERFAEVPDE NIVKVSHIYA EYVTSEANLR FAMNNHAVTE
     GGVRPEEQPE VPIVPVEPVR PVRPVRPVRP VRPVDPSPGG VRPIVPEEFE PTKPTFTEPM
     TVCERELQEA ERMRDLGKEI ADEIFFPTCT NLGTFAPRQC TTYDSVCWCV DQDSGVEIDG
     TRSLPREGYG LDCSDVRPPP PSQTPCEEDR TIAENARNRA GSEANSIFMP RCMESGAYEP
     VQQLPDGTFM CVDFDGEEIS RSREEPRCLT SCQLQAYVAE SNNIFKDTSL FVVQCKPDGE
     YLPRQCVASY CFCVDRNGLE ISNSRVETRI AGIGVDLDCQ DFNEPIIPDI VVPEVVVTQV
     PDREPEVPRQ RIPESGKLIF AQSMGINIAD LPITRETAAQ RLYGRYDQTP IGLTYDCTNK
     MYYWSSVVKR AIYSAELEGD GSHSVIVNSK LRSPEGIAVD FISGNLYWAD SEYDRIEVSN
     TDGSNRMTLI DEGLMNPRGI AVDPFHGRLY WTDWYRKSPK IMMADMDGSN VQTIASEGLE
     LPNDITIDFY NEKVCFIDAG TKRVECMNLD GSGRRTIYVL PSPPKQHPFG LAIDGDVLFY
     STWRGSKEVH AVNWRTGDNV AISGPRGTHG QTYGIAVVHS QCPRGYNYCG QDNGGCSHLC
     LPTPYGRVCK CPPDAFGCTS K
//