ID   Q04NN7_LEPBJ            Unreviewed;       325 AA.
AC   Q04NN7;
DT   14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   14-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   SubName: Full=Transcriptional regulator, ArsR family {ECO:0000313|EMBL:ABJ77483.1};
GN   OrderedLocusNames=LBJ_4088 {ECO:0000313|EMBL:ABJ77483.1};
OS   Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197).
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=355277 {ECO:0000313|EMBL:ABJ77483.1, ECO:0000313|Proteomes:UP000000656};
RN   [1] {ECO:0000313|EMBL:ABJ77483.1, ECO:0000313|Proteomes:UP000000656}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JB197 {ECO:0000313|EMBL:ABJ77483.1,
RC   ECO:0000313|Proteomes:UP000000656};
RX   PubMed=16973745; DOI=10.1073/pnas.0603979103;
RA   Bulach D.M., Zuerner R.L., Wilson P., Seemann T., McGrath A., Cullen P.A.,
RA   Davis J., Johnson M., Kuczek E., Alt D.P., Peterson-Burch B., Coppel R.L.,
RA   Rood J.I., Davies J.K., Adler B.;
RT   "Genome reduction in Leptospira borgpetersenii reflects limited
RT   transmission potential.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:14560-14565(2006).
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DR   EMBL; CP000351; ABJ77483.1; -; Genomic_DNA.
DR   RefSeq; WP_002756542.1; NC_008511.1.
DR   AlphaFoldDB; Q04NN7; -.
DR   KEGG; lbj:LBJ_4088; -.
DR   PATRIC; fig|355276.3.peg.4056; -.
DR   HOGENOM; CLU_063642_1_0_12; -.
DR   Proteomes; UP000000656; Chromosome 2.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; NF033788; HTH_metalloreg; 1.
DR   PANTHER; PTHR42912; METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR42912:SF107; METHYLTRANSFERASE-LIKE PROTEIN 7A-RELATED; 1.
DR   Pfam; PF01022; HTH_5; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   PRINTS; PR00778; HTHARSR.
DR   SMART; SM00418; HTH_ARSR; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50987; HTH_ARSR_2; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          9..103
FT                   /note="HTH arsR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50987"
SQ   SEQUENCE   325 AA;  36820 MW;  A0293E913CB46011 CRC64;
     MKLLEAKIVS GNGPKQILSA LKALSDETRI RILHILSLSP LNVQEITEVL KMGQSRVSRH
     LKILTDAGFL VPEREGSWVY YRIPEEKKAS VFSSEVTELL LSYKEDLPFR TIDQAQIAEI
     LSRRDQKSTF YFNNVAHDWE SIQKDVLDPA IYRKKILSYL PDFSSLVYDL GCGPGGLIPY
     LLTKSDQVIG VDASPKMVEE AEVTFTGNAH VSLICSPLED LASYAREEAD AVVASMVLHH
     LSNPPAVIRE IYKILKPDGT FCLVDLKKHN QEFMRDNFSD LWLGFDYSLL QDWLELSGFR
     VGSYEEFDTG NVFKILIIQA KKKED
//