ID   Q05504_MOUSE            Unreviewed;       959 AA.
AC   Q05504;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Collagen alpha 3 chain type VI {ECO:0000313|EMBL:CAA79156.1};
DE   Flags: Fragment;
GN   Name=Col6a3 {ECO:0000313|MGI:MGI:88461};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:CAA79156.1};
RN   [1] {ECO:0000313|EMBL:CAA79156.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Chu M.;
RL   Submitted (OCT-1992) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CAA79156.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8489506;
RA   Zhang R.Z., Pan T.C., Timpl R., Chu M.L.;
RT   "Cloning and sequence analysis of cDNAs encoding the alpha 1, alpha 2 and
RT   alpha 3 chains of mouse collagen VI.";
RL   Biochem. J. 291:787-792(1993).
CC   -!- FUNCTION: Collagen VI acts as a cell-binding protein.
CC       {ECO:0000256|ARBA:ARBA00043858}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
CC   -!- SIMILARITY: Belongs to the type VI collagen family.
CC       {ECO:0000256|ARBA:ARBA00044000}.
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DR   EMBL; Z18279; CAA79156.1; -; mRNA.
DR   PIR; S32605; S32605.
DR   IntAct; Q05504; 3.
DR   PeptideAtlas; Q05504; -.
DR   UCSC; uc007bzk.1; mouse.
DR   AGR; MGI:88461; -.
DR   MGI; MGI:88461; Col6a3.
DR   ChiTaRS; Col6a3; mouse.
DR   GO; GO:0005581; C:collagen trimer; IDA:MGI.
DR   GO; GO:0062023; C:collagen-containing extracellular matrix; IBA:GO_Central.
DR   GO; GO:0031012; C:extracellular matrix; IDA:MGI.
DR   GO; GO:0005615; C:extracellular space; IDA:MGI.
DR   GO; GO:0042383; C:sarcolemma; IDA:MGI.
DR   GO; GO:0051402; P:neuron apoptotic process; IDA:MGI.
DR   GO; GO:0043491; P:phosphatidylinositol 3-kinase/protein kinase B signal transduction; IDA:MGI.
DR   GO; GO:0009411; P:response to UV; IDA:MGI.
DR   CDD; cd01450; vWFA_subfamily_ECM; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 3.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR22588:SF5; COLLAGEN ALPHA-6(VI) CHAIN; 1.
DR   PANTHER; PTHR22588; UNCHARACTERIZED; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   Pfam; PF00092; VWA; 2.
DR   SMART; SM00327; VWA; 3.
DR   SUPFAM; SSF53300; vWA-like; 3.
DR   PROSITE; PS50234; VWFA; 3.
PE   2: Evidence at transcript level;
KW   Collagen {ECO:0000313|EMBL:CAA79156.1}.
FT   DOMAIN          1..126
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          148..334
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          712..891
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          351..683
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..434
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..479
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        601..623
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAA79156.1"
FT   NON_TER         959
FT                   /evidence="ECO:0000313|EMBL:CAA79156.1"
SQ   SEQUENCE   959 AA;  101758 MW;  AE483BC7F14A3876 CRC64;
     FFLRDFSTKR QIIDAINKVV YKGGRHANTR VGIEHLLRNH FVPEAGSRLD ERVPQIAFVI
     TGGKSVEDAQ DVSLALTQKG VKVFAVGVRN IDSEEVGKIA SNSATAFRVG SVQELSELSE
     TVLETLHDAM HETLCPGVTD VSKACNLEVI LGFDGSRDQN VFVSQKGLES KVDIILNRIS
     QIQRISCSGN QLPTVRVSVM ANTPSGPVEA FDFAEYQPEL FEKFRNMRSQ RPYVLTADTL
     KLYQNKFRQS SPDTVKVVIH FTDGADGDMA DLYRASEELR QAGAQALILV GLERVANLER
     LMHLEFGRGF MYDRPLRLNQ LDLDYELAEQ LDNIAEKACC GVPCKCSGER GDRGPIGSIG
     PKGISGEDGY RGYPGDEGDP GERGPPGVNG TQGFQGCPGQ RGVKGSRGFP GEKGELGEIG
     LDGLDGEEGD KGLPGSSGEK GSPGRRGDKG PKGDKGERGD VGIRGDPGDS GRDSQQRGPK
     GETGDIGPMG LPGRDGIPGS PGDPGKDGGS GRRGPAGAKG NRGGPGQPGF EGEQGTRGSQ
     GPPGPIGPPG LIGEQXXXGP RGGGGTAGAP GERGRTGPLG RKGEPGEPGP KGSIGNRGPR
     GETGDDGRDG VGSEGRRGKK GERGFPGYPG PKGTPGEPGA DGPPGPKGIR GRRGNSGPPG
     ATGQKGDPGY PGPSGHKGNR GDSVDQCALI QSIRDKCPCC YGPLECPVLP TELAFALDTS
     EGVTQDTFSR MREVLLGIVG DLTIAESNCP RGARVAVVTY NNEVTTEIRF ASSKKKSALL
     DSIQNLQVAL TSKQQSLETA MSFVARNTFK RVRSGFPMRK VAVFFSNKPT RASPQLREAV
     LKLSDAGITP LFLTSQEDRQ LINALQINNT AVGHALVLPA RRDLTDFLKN VLTCHVCLDI
     CNIDPSCGFG SWRPSFRDRR AAGSDVDIDL AFILDSSEAT TLFQFNEMKK YIGYVIRQL
//