ID Q06L87_9LAMI Unreviewed; 252 AA.
AC Q06L87;
DT 31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=chalcone synthase {ECO:0000256|ARBA:ARBA00012975};
DE EC=2.3.1.74 {ECO:0000256|ARBA:ARBA00012975};
DE Flags: Fragment;
GN Name=CHS-D {ECO:0000313|EMBL:ABH05777.1};
OS Streptocarpus brevipilosus.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae;
OC Streptocarpinae; Streptocarpus; Streptocarpus subgen. Streptocarpella;
OC Streptocarpus sect. Saintpaulia.
OX NCBI_TaxID=86140 {ECO:0000313|EMBL:ABH05777.1};
RN [1] {ECO:0000313|EMBL:ABH05777.1}
RP NUCLEOTIDE SEQUENCE.
RA Kotarski M.A., Sweeney C.S., Caro S.E., Stampfle J.M., Greene M.J.,
RA Leonard D.A.;
RT "Phylogeny of Saintpaulia (Gesneriaceae) inferred from chalcone synthase
RT nuclear gene sequences.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The primary product of this enzyme is 4,2',4',6'-
CC tetrahydroxychalcone (also termed naringenin-chalcone or chalcone)
CC which can under specific conditions spontaneously isomerize into
CC naringenin. {ECO:0000256|ARBA:ARBA00002969}.
CC -!- PATHWAY: Secondary metabolite biosynthesis; flavonoid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004966}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; DQ788920; ABH05777.1; -; Genomic_DNA.
DR AlphaFoldDB; Q06L87; -.
DR UniPathway; UPA00154; -.
DR GO; GO:0102128; F:chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016210; F:naringenin-chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF14; CHALCONE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003633};
KW Flavonoid biosynthesis {ECO:0000256|ARBA:ARBA00023241};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 1..122
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 132..251
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABH05777.1"
FT NON_TER 252
FT /evidence="ECO:0000313|EMBL:ABH05777.1"
SQ SEQUENCE 252 AA; 27232 MW; B3E3E4A734724E45 CRC64;
KDAAQKAIKE WGQPKSKITH VVFCTTSGVD MPGADYQLTK LLGLRASVKR FMMYQQGCFA
GGTVLRMAKD LAENNAGARV LVVCSEITAV TFRGPSETHL DSLVGQALFG DGAAAVIVGS
DPVIGVERPL FQLVSAAQTI LPDSHGAIDG HLREEGLTFH LLKDVPSLIS QNIEKSLREA
FDPLGISDWN SVFWIAHPGG PAILDQVESK LALKPEKLRS TRHVLSEYGN MSSACVLFIL
DEMRMDSAKE GL
//
