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Database: UniProt
Entry: Q07041_VARV
LinkDB: Q07041_VARV
Original site: Q07041_VARV 
ID   Q07041_VARV             Unreviewed;       585 AA.
AC   Q07041;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   01-OCT-2014, entry version 78.
DE   SubName: Full=Ankyrin-like protein {ECO:0000313|EMBL:ABF23163.1};
DE   SubName: Full=B25-27R COP protein {ECO:0000313|EMBL:CAA47539.1};
DE   SubName: Full=G1R {ECO:0000313|EMBL:AAA69466.1};
GN   Name=B25-27R COP {ECO:0000313|EMBL:CAA47539.1};
GN   ORFNames=VARV_AFG70_vlt4_204 {ECO:0000313|EMBL:ABG43366.1},
GN   VARV_BOT72_143_204 {ECO:0000313|EMBL:ABF23163.1}, VARV_BOT73_225_204
GN   {ECO:0000313|EMBL:ABF23364.1}, VARV_BSH74_nur_204
GN   {ECO:0000313|EMBL:ABF23767.1}, VARV_BSH74_shz_204
GN   {ECO:0000313|EMBL:ABF23964.1}, VARV_BSH74_sol_204
GN   {ECO:0000313|EMBL:ABF24161.1}, VARV_BSH75_banu_204
GN   {ECO:0000313|EMBL:ABG43567.1}, VARV_CHN48_horn_204
GN   {ECO:0000313|EMBL:ABG43770.1}, VARV_CNG70_227_204
GN   {ECO:0000313|EMBL:ABF24361.1}, VARV_CNG70_46_204
GN   {ECO:0000313|EMBL:ABG43974.1}, VARV_ETH72_16_204
GN   {ECO:0000313|EMBL:ABF24563.1}, VARV_ETH72_17_204
GN   {ECO:0000313|EMBL:ABF24764.1}, VARV_GER58_hdlg_204
GN   {ECO:0000313|EMBL:ABG44175.1}, VARV_IND53_mad_204
GN   {ECO:0000313|EMBL:ABF25168.1}, VARV_IND64_vel4_204
GN   {ECO:0000313|EMBL:ABG44380.1}, VARV_IND64_vel5_204
GN   {ECO:0000313|EMBL:ABG44582.1}, VARV_KOR47_lee_204
GN   {ECO:0000313|EMBL:ABF26176.1}, VARV_KUW67_1629_204
GN   {ECO:0000313|EMBL:ABF26375.1}, VARV_NEP73_175_204
GN   {ECO:0000313|EMBL:ABG44986.1}, VARV_PAK69_lah_204
GN   {ECO:0000313|EMBL:ABG45190.1}, VARV_SAF65_103_204
GN   {ECO:0000313|EMBL:ABF26981.1}, VARV_SOM77_1252_204
GN   {ECO:0000313|EMBL:ABF27384.1}, VARV_SOM77_1605_204
GN   {ECO:0000313|EMBL:ABF27583.1}, VARV_SOM77_ali_204
GN   {ECO:0000313|EMBL:ABG45392.1}, VARV_SUD47_jub_204
GN   {ECO:0000313|EMBL:ABF27783.1}, VARV_SUD47_rum_204
GN   {ECO:0000313|EMBL:ABF27983.1}, VARV_SUM70_222_204
GN   {ECO:0000313|EMBL:ABG45593.1}, VARV_SYR72_119_204
GN   {ECO:0000313|EMBL:ABG45797.1}, VARV_UNK44_harv_204
GN   {ECO:0000313|EMBL:ABF28582.1}, VARV_UNK46_hind_204
GN   {ECO:0000313|EMBL:ABF28780.1}, VARV_UNK47_hig_204
GN   {ECO:0000313|EMBL:ABF28980.1}, VARV_YUG72_164_204
GN   {ECO:0000313|EMBL:ABF29388.1};
OS   Variola virus.
OC   Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae;
OC   Orthopoxvirus.
OX   NCBI_TaxID=10255 {ECO:0000313|EMBL:CAA47539.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:CAA47539.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=India-1967 {ECO:0000313|EMBL:CAA47539.1};
RA   Shchelkunov S.N., Marennikova S.S., Totmenin A.V., Blinov V.M.,
RA   Chizhikov V.E., Gutorov V.V., Safronov P.F., Pozdnyakov S.G.,
RA   Shelukhina E.M., Gashnikov P.V., Anjaparidze O.G., Sandakhchiev L.S.;
RT   "Constructions of clonoteques of the genomic fragments of poxvirus and
RT   study of structural and functional organization of host range viral
RT   genes.";
RL   Dokl. Akad. Nauk SSSR 321:404-406(1991).
RN   [2] {ECO:0000313|EMBL:CAA47539.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=India-1967 {ECO:0000313|EMBL:CAA47539.1};
RA   Kolykhalov A.A., Blinov V.M., Gytorov V.V., Pozdnyakov S.G.,
RA   Chizhikov V.E., Frolov I.V., Totmenin A.V., Shchelkunov S.N.,
RA   Sandakhchiev L.S.;
RT   "Nucleotide sequence analysis of the region of Variola virus XhoI F O
RT   H P Q genome fragment.";
RL   Submitted (APR-1992) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AAA69466.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Somalia-1977 {ECO:0000313|EMBL:AAA69466.1};
RX   PubMed=8661439; DOI=10.1006/viro.1996.0378;
RA   Massung R.F., Loparev V.N., Knight J.C., Totmenin A.V.,
RA   Chizhikov V.E., Parsons J.M., Safronov P.F., Gutorov V.V.,
RA   Shchelkunov S.N., Esposito J.J.;
RT   "Terminal region sequence variations in variola virus DNA.";
RL   Virology 221:291-300(1996).
RN   [4] {ECO:0000313|EMBL:ABF23163.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Afghanistan 1970 Variolator 4 {ECO:0000313|EMBL:ABG43366.1},
RC   Bangladesh 1974 {ECO:0000313|EMBL:ABF23767.1}, Bangladesh 1975 v75-550
RC   Banu {ECO:0000313|EMBL:ABG43567.1}, Botswana 1972
RC   {ECO:0000313|EMBL:ABF23163.1}, Botswana 1973
RC   {ECO:0000313|EMBL:ABF23364.1}, China Horn 1948
RC   {ECO:0000313|EMBL:ABG43770.1}, Congo 1970 v70-46 Kinshasa
RC   {ECO:0000313|EMBL:ABG43974.1}, Congo 9 1970
RC   {ECO:0000313|EMBL:ABF24361.1}, Ethiopia 1972
RC   {ECO:0000313|EMBL:ABF24563.1}, Germany 1958 Heidelberg
RC   {ECO:0000313|EMBL:ABG44175.1}, India 1953
RC   {ECO:0000313|EMBL:ABF25168.1}, India 1964 7124 Vellore
RC   {ECO:0000313|EMBL:ABG44380.1}, India 1964 7125 Vellore
RC   {ECO:0000313|EMBL:ABG44582.1}, Korea 1947
RC   {ECO:0000313|EMBL:ABF26176.1}, Kuwait 1967
RC   {ECO:0000313|EMBL:ABF26375.1}, Nepal 1973 V73-175
RC   {ECO:0000313|EMBL:ABG44986.1}, Pakistan 1969
RC   {ECO:0000313|EMBL:ABG45190.1}, Somalia 1977
RC   {ECO:0000313|EMBL:ABF27384.1}, South Africa 1965
RC   {ECO:0000313|EMBL:ABF26981.1}, Sudan 1947
RC   {ECO:0000313|EMBL:ABF27783.1}, Sumatra 1970 V70-222
RC   {ECO:0000313|EMBL:ABG45593.1}, Syria 1972 V72-199
RC   {ECO:0000313|EMBL:ABG45797.1}, United Kingdom 1946 Harvey
RC   {ECO:0000313|EMBL:ABF28582.1}, United Kingdom 1946 Hinden
RC   {ECO:0000313|EMBL:ABF28780.1}, United Kingdom 1947 Higgins
RC   {ECO:0000313|EMBL:ABF28980.1}, and Yugoslavia 1972 V72-164
RC   {ECO:0000313|EMBL:ABF29388.1};
RX   PubMed=16873609; DOI=10.1126/science.1125134;
RA   Esposito J.J., Sammons S.A., Frace A.M., Osborne J.D.,
RA   Olsen-Rasmussen M., Zhang M., Govil D., Damon I.K., Kline R.,
RA   Laker M., Li Y., Smith G.L., Meyer H., Leduc J.W., Wohlhueter R.M.;
RT   "Genome sequence diversity and clues to the evolution of variola
RT   (smallpox) virus.";
RL   Science 313:807-812(2006).
CC   -!- SIMILARITY: Contains 6 ANK repeats.
CC       {ECO:0000256|RuleBase:RU003321}.
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DR   EMBL; U18341; AAA69466.1; -; Genomic_DNA.
DR   EMBL; DQ441417; ABF23163.1; -; Genomic_DNA.
DR   EMBL; DQ441418; ABF23364.1; -; Genomic_DNA.
DR   EMBL; DQ441420; ABF23767.1; -; Genomic_DNA.
DR   EMBL; DQ441421; ABF23964.1; -; Genomic_DNA.
DR   EMBL; DQ441422; ABF24161.1; -; Genomic_DNA.
DR   EMBL; DQ441423; ABF24361.1; -; Genomic_DNA.
DR   EMBL; DQ441424; ABF24563.1; -; Genomic_DNA.
DR   EMBL; DQ441425; ABF24764.1; -; Genomic_DNA.
DR   EMBL; DQ441427; ABF25168.1; -; Genomic_DNA.
DR   EMBL; DQ441432; ABF26176.1; -; Genomic_DNA.
DR   EMBL; DQ441433; ABF26375.1; -; Genomic_DNA.
DR   EMBL; DQ441436; ABF26981.1; -; Genomic_DNA.
DR   EMBL; DQ441438; ABF27384.1; -; Genomic_DNA.
DR   EMBL; DQ441439; ABF27583.1; -; Genomic_DNA.
DR   EMBL; DQ441440; ABF27783.1; -; Genomic_DNA.
DR   EMBL; DQ441441; ABF27983.1; -; Genomic_DNA.
DR   EMBL; DQ441444; ABF28582.1; -; Genomic_DNA.
DR   EMBL; DQ441445; ABF28780.1; -; Genomic_DNA.
DR   EMBL; DQ441446; ABF28980.1; -; Genomic_DNA.
DR   EMBL; DQ441448; ABF29388.1; -; Genomic_DNA.
DR   EMBL; DQ437580; ABG43366.1; -; Genomic_DNA.
DR   EMBL; DQ437581; ABG43567.1; -; Genomic_DNA.
DR   EMBL; DQ437582; ABG43770.1; -; Genomic_DNA.
DR   EMBL; DQ437583; ABG43974.1; -; Genomic_DNA.
DR   EMBL; DQ437584; ABG44175.1; -; Genomic_DNA.
DR   EMBL; DQ437585; ABG44380.1; -; Genomic_DNA.
DR   EMBL; DQ437586; ABG44582.1; -; Genomic_DNA.
DR   EMBL; DQ437588; ABG44986.1; -; Genomic_DNA.
DR   EMBL; DQ437589; ABG45190.1; -; Genomic_DNA.
DR   EMBL; DQ437590; ABG45392.1; -; Genomic_DNA.
DR   EMBL; DQ437591; ABG45593.1; -; Genomic_DNA.
DR   EMBL; DQ437592; ABG45797.1; -; Genomic_DNA.
DR   EMBL; X67117; CAA47539.1; -; Genomic_DNA.
DR   PIR; C36858; C36858.
DR   PIR; T28622; T28622.
DR   RefSeq; NP_042239.1; NC_001611.1.
DR   ProteinModelPortal; Q07041; -.
DR   GeneID; 1486426; -.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR018272; PRANC_domain.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF09372; PRANC; 1.
DR   SMART; SM00248; ANK; 6.
DR   SUPFAM; SSF48403; SSF48403; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|RuleBase:RU003321};
KW   Repeat {ECO:0000256|RuleBase:RU003536}.
SQ   SEQUENCE   585 AA;  69057 MW;  E471FE00AEB99A71 CRC64;
     MDEIVNIVRD SMWFIPNVFM DNGENDGHVS VNNVCHMYFA FFDVDTSSHL FKLVIKHCDL
     NKQLKCGMSP LHCYVMNTRF KPSVLKILLH NGVNNFDNKD NKGHIPLHHY LIYSLSIDNK
     VFDILTDPID DFSKSSDLLL CYLRYKFNGR LNYYVLYKLL TKGSDPNCVD EDGLTSLHYY
     CKHISAFHES NYYKSKSYTK MRAEKRFIYT IINHGANINA VTKIGNTPLH TYLQQYTKHS
     PRVVYALLSR GADTRIRNNF DCTPIMEYIK NDCVTGHILI MLLNWHEQKY GKLQKEEGHH
     LLYLFIKHNQ GYGSHAFNIL RYLLDRFDIQ KDEYYNTMTP LHTAFQNCNN NVASYLVYIG
     YDINLPTKDD KTVFDLVFEN RNILFNAGVI HNIIHHRLKV SLPMIKSLFY KMLEFSPYDD
     YYVKKIIAYC ILRDESFTEL HSKFCLNEDY KSVFMKNISF DKIDSIIKKC NWDISRLKDI
     QISDTNLYTV LRTEDIRYRT YLKAIHLDSH ISFPMYDDLI EQCHLSMERK SKLVDKVLNK
     LKSTIDGQSR LSYLPPEIIR NIITKLSDYH LNSMLYGKNH YKYYT
//
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