ID Q071I8_TASV1 Unreviewed; 171 AA.
AC Q071I8;
DT 31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2006, sequence version 1.
DT 08-NOV-2023, entry version 66.
DE RecName: Full=Non-structural polyprotein 1AB {ECO:0000256|ARBA:ARBA00019743};
DE Flags: Fragment;
OS Turkey astrovirus 1 (TAstV-1).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC Stellavirales; Astroviridae; Avastrovirus; Avastrovirus 1.
OX NCBI_TaxID=364370 {ECO:0000313|EMBL:ABC60196.1};
OH NCBI_TaxID=9103; Meleagris gallopavo (Wild turkey).
RN [1] {ECO:0000313|EMBL:ABC60196.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MO-SEP-A823-05 {ECO:0000313|EMBL:ABC60196.1};
RX PubMed=17039840; DOI=10.1637/7512-020606R.1;
RA Pantin-Jackwood M.J., Spackman E., Woolcock P.R.;
RT "Molecular characterization and typing of chicken and turkey astroviruses
RT circulating in the United States: implications for diagnostics.";
RL Avian Dis. 50:397-404(2006).
CC -!- FUNCTION: Contains the viral protease participating in the cleavage of
CC the polyprotein into functional products. It contains also the
CC activities necessary for replication of genomic RNA, as well as
CC transcription of subgenomic mRNA. {ECO:0000256|ARBA:ARBA00029407}.
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000256|ARBA:ARBA00004301};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004301}.
CC -!- SIMILARITY: Belongs to the astroviridae polyprotein 1AB family.
CC {ECO:0000256|ARBA:ARBA00005873}.
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DR EMBL; DQ324825; ABC60196.1; -; Genomic_RNA.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR CDD; cd23172; ps-ssRNAv_Astroviridae_RdRp; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Ribosomal frameshifting {ECO:0000256|ARBA:ARBA00022758};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 50..171
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABC60196.1"
FT NON_TER 171
FT /evidence="ECO:0000313|EMBL:ABC60196.1"
SQ SEQUENCE 171 AA; 20270 MW; A272CC54F994469C CRC64;
PVFTRIGAAF EQHQNSLMKL ETENHHAQVG WSPFFGGIHR RATRLYGEHR YYVELDWTRF
DGTIPPELFR RIKLMRFFLL DPKHKTPENR DRYNWYVENL IDKVVLLPTG EVCKIYGGNP
SGQFSTTVDN NFVNVWLTVF ELAYLFYKEH NRLPTISEIK KHTGWICYGD D
//
