ID Q08DU0_BOVIN Unreviewed; 343 AA.
AC Q08DU0;
DT 31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Protease, serine, 8 {ECO:0000313|EMBL:AAI23569.1};
GN Name=PRSS8 {ECO:0000313|EMBL:AAI23569.1};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI23569.1};
RN [1] {ECO:0000313|EMBL:AAI23569.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI23569.1};
RC TISSUE=Fetal lung {ECO:0000313|EMBL:AAI23569.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BC123568; AAI23569.1; -; mRNA.
DR RefSeq; NP_001070399.1; NM_001076931.1.
DR AlphaFoldDB; Q08DU0; -.
DR MEROPS; S01.159; -.
DR GeneID; 613506; -.
DR KEGG; bta:613506; -.
DR CTD; 5652; -.
DR OrthoDB; 4629979at2759; -.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24253:SF159; PROSTASIN; 1.
DR PANTHER; PTHR24253; TRANSMEMBRANE PROTEASE SERINE; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034, ECO:0000313|EMBL:AAI23569.1};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..343
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004166661"
FT DOMAIN 46..287
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 343 AA; 36709 MW; 9F22587E2A913603 CRC64;
MARKSGVGPR WLEAVATVLL LGLFRNGIGA VVAEADSCGM VPQGRITGGT TAALGQWPWQ
VSINHHGTHV CGGSLVSDQW VLSAAHCFPS DNKIEEYEVK LGAHQLDYFS TDTQVRGVAQ
VISHEKYSHE GSMGDIALLQ LSSSVTFSRY IRPICLPAAN ASFPNGLQCV VTGWGHVAPS
VSLQHPRPLQ QLEVPLISRE TCNCLYNINA KPGEPHVIDQ DMLCAGYVNG SKDACQGDSG
GPLSCPVAGR WYLAGIVSWG DACGAPNRPG VYTLTSVYAS WIHYKVAELQ PKVVPQMEES
QPDGHLCSHY KGFNSAPAQG LVGPILLLPL GLTLGLLRPL HED
//
