ID Q0A5T0_ALKEH Unreviewed; 792 AA.
AC Q0A5T0;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Exporters of the RND superfamily {ECO:0000313|EMBL:ABI57807.1};
GN OrderedLocusNames=Mlg_2467 {ECO:0000313|EMBL:ABI57807.1};
OS Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Alkalilimnicola.
OX NCBI_TaxID=187272 {ECO:0000313|EMBL:ABI57807.1, ECO:0000313|Proteomes:UP000001962};
RN [1] {ECO:0000313|Proteomes:UP000001962}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1101 / DSM 17681 / MLHE-1
RC {ECO:0000313|Proteomes:UP000001962};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Oremland R.S.,
RA Hoeft S.E., Switzer-Blum J., Kulp T., King G., Tabita R., Witte B.,
RA Santini J.M., Basu P., Hollibaugh J.T., Xie G., Stolz J.F., Richardson P.;
RT "Complete sequence of Alkalilimnicola ehrilichei MLHE-1.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000453; ABI57807.1; -; Genomic_DNA.
DR RefSeq; WP_011630200.1; NC_008340.1.
DR AlphaFoldDB; Q0A5T0; -.
DR KEGG; aeh:Mlg_2467; -.
DR eggNOG; COG1033; Bacteria.
DR HOGENOM; CLU_008861_4_0_6; -.
DR OrthoDB; 9803781at2; -.
DR Proteomes; UP000001962; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF10; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001962};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 665..682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..727
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 55..385
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 526..763
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 792 AA; 86836 MW; DECE90237218AA6D CRC64;
MVQRFADLCI QLRAWLVGVL AFLTLFHAWN ALNINVETVF EDLLPQSHPY VETHEQFKDA
FGSSNMVTIM IEPVEGDIFQ TEVLRKVQFL TRELRTVPAV DDYQIVSLAA RKLKEVTGST
AGIDTRSLMW PDVPTTQAGL DQLREAVVTN PVVMGTYVSE DLSSTLITAD FIDHLVDYEV
VFNEIRALID QVDDASVQVR LVGDPILYGW VNHYLSETLQ LAMLALLVMA VVLFALVRTW
RGTLLPLISG FASGSWALGT ASLLGIHFDP LVVVVAVLIT SRAVSHSVQI VTRFEEELAK
LGDAPAASRQ AASNTLRELF RPGLLGIATD AGCVAVVALS PIPLLQKLAF MAITWISTVA
VSAIILTPVL LSWVSQARVQ TRRRLDPLRP VLNLALRTVA GRARVPALVT ALVVLLGSGY
FAFGLQVGDA NPGSPILWPD STYNQDSAAV NANYHGADRM FIVASGEEEG FVQRPEVLTN
MNRLQRFMEA QPQVGGTLSV ADILPTVHRV LREGNPHYQE LPNDALMTGE LMYIFESVSE
PGDLDQFVDS DKKNASITLF FRDRQGDTIR TALARLNEYI DNNPLQGGEY LLAGGLIGLL
GAVNEVILAG QIQSIALALL VLVVMCTLVY RSSMAGMFFM VPVIMSNTLT FSFMAWQGIG
MNINTVPVAA LGIGLGVDYA LYICDRIREE LRRSGDELRA YRLALHSAGR AVLITAAVLI
ASTLLWWASS LRFQAEMGLL MGLWLTVSAV TALFVMPSLA YVFKPRFIYR DFQPEPRQEA
AASGDRLVPN EG
//
