ID Q0AG69_NITEC Unreviewed; 452 AA.
AC Q0AG69;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Two component, sigma54 specific, transcriptional regulator, Fis family protein {ECO:0000313|EMBL:ABI59663.1};
GN OrderedLocusNames=Neut_1416 {ECO:0000313|EMBL:ABI59663.1};
OS Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=335283 {ECO:0000313|EMBL:ABI59663.1, ECO:0000313|Proteomes:UP000001966};
RN [1] {ECO:0000313|EMBL:ABI59663.1, ECO:0000313|Proteomes:UP000001966}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 101675 / C91 / Nm57 {ECO:0000313|Proteomes:UP000001966};
RX PubMed=17991028; DOI=10.1111/j.1462-2920.2007.01409.x;
RA Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S.,
RA Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M., Wei X.;
RT "Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas
RT eutropha C91: implications for niche adaptation.";
RL Environ. Microbiol. 9:2993-3007(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000450; ABI59663.1; -; Genomic_DNA.
DR RefSeq; WP_011634469.1; NC_008344.1.
DR AlphaFoldDB; Q0AG69; -.
DR STRING; 335283.Neut_1416; -.
DR KEGG; net:Neut_1416; -.
DR eggNOG; COG2204; Bacteria.
DR HOGENOM; CLU_000445_0_6_4; -.
DR OrthoDB; 5288224at2; -.
DR Proteomes; UP000001966; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014264; PEP-CTERM_resp_reg.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR NCBIfam; TIGR02915; PEP_resp_reg; 1.
DR PANTHER; PTHR32071:SF113; HYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN HOXA; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..126
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 150..379
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT MOD_RES 56
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 452 AA; 50090 MW; ED7A7BC42D9EB43E CRC64;
MKANEIQKKL LVVEDDPGLQ KQLRWSFDDC NVAVASDRES ALAQIRRHEP AVVTMDLGLP
PDPDGATEGL ATLQQILALA PDTKVIVLTG NQNHENALKA IDMGAYDFHQ KPLDAGVLNL
IVNRAFYLHR LQRENYKLRQ AGLISSVPGF ITGDPEIARI CQQIERIASS DVAVALLGES
GTGKEVLAKA LHLLSGRNSK RMVAVNCAAI PESLLEAELF GYEKGAFTNA AKQTLGKIET
AQGGTFFLDE VGDLPLSLQA KLLRFLQERV IERIGGREEI PVDVRIICAT HQDLKKMIDA
GTFREDLFYR LCEISIHIPP VRERIGDAVL LAHHFKNQYR IKEKRQTLNF SQDALNAISS
HRWPGNVREI ENCIKRAVIM AEGSQITAQD LGLQSADNPE QPATLREVRE QAEREVVAKA
LARMDGNIVK AAELLGVTRP TLYDLMNRHG LK
//
