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Database: UniProt
Entry: Q0AGZ9
LinkDB: Q0AGZ9
Original site: Q0AGZ9 
ID   UBIA_NITEC              Reviewed;         286 AA.
AC   Q0AGZ9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   26-NOV-2014, entry version 63.
DE   RecName: Full=4-hydroxybenzoate octaprenyltransferase {ECO:0000255|HAMAP-Rule:MF_01635};
DE            EC=2.5.1.- {ECO:0000255|HAMAP-Rule:MF_01635};
DE   AltName: Full=4-HB polyprenyltransferase {ECO:0000255|HAMAP-Rule:MF_01635};
GN   Name=ubiA {ECO:0000255|HAMAP-Rule:MF_01635};
GN   OrderedLocusNames=Neut_1128;
OS   Nitrosomonas eutropha (strain C91).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=335283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C91;
RX   PubMed=17991028; DOI=10.1111/j.1462-2920.2007.01409.x;
RA   Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S.,
RA   Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M.,
RA   Wei X.;
RT   "Whole-genome analysis of the ammonia-oxidizing bacterium,
RT   Nitrosomonas eutropha C91: implications for niche adaptation.";
RL   Environ. Microbiol. 9:2993-3007(2007).
CC   -!- FUNCTION: Synthesis of 3-octaprenyl-4-hydroxybenzoate.
CC       {ECO:0000255|HAMAP-Rule:MF_01635}.
CC   -!- CATALYTIC ACTIVITY: 4-hydroxybenzoate + farnesylfarnesylgeraniol =
CC       3-octaprenyl-4-hydroxybenzoate. {ECO:0000255|HAMAP-Rule:MF_01635}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01635};
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01635}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01635}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01635}.
CC   -!- SIMILARITY: Belongs to the UbiA prenyltransferase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01635}.
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DR   EMBL; CP000450; ABI59383.1; -; Genomic_DNA.
DR   RefSeq; YP_747348.1; NC_008344.1.
DR   STRING; 335283.Neut_1128; -.
DR   EnsemblBacteria; ABI59383; ABI59383; Neut_1128.
DR   GeneID; 4272410; -.
DR   KEGG; net:Neut_1128; -.
DR   PATRIC; 22719517; VBINitEut7577_1423.
DR   eggNOG; COG0382; -.
DR   HOGENOM; HOG000003696; -.
DR   KO; K03179; -.
DR   OMA; AWSDTQN; -.
DR   OrthoDB; EOG680X3B; -.
DR   BioCyc; NEUT335283:GHT6-1150-MONOMER; -.
DR   UniPathway; UPA00232; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004659; F:prenyltransferase activity; IEA:InterPro.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01635; UbiA; 1.
DR   InterPro; IPR006370; HB_polyprenyl-transferase.
DR   InterPro; IPR000537; UbiA_prenyltransferase.
DR   Pfam; PF01040; UbiA; 1.
DR   TIGRFAMs; TIGR01474; ubiA_proteo; 1.
DR   PROSITE; PS00943; UBIA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Magnesium;
KW   Membrane; Transferase; Transmembrane; Transmembrane helix;
KW   Ubiquinone biosynthesis.
FT   CHAIN         1    286       4-hydroxybenzoate octaprenyltransferase.
FT                                /FTId=PRO_1000069826.
FT   TRANSMEM     20     40       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM     43     63       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM     83    103       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    105    125       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    135    155       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    160    180       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    209    229       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    234    254       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
SQ   SEQUENCE   286 AA;  31507 MW;  774F1CB988AAB4D7 CRC64;
     MTFSERFSAY ARLTRLDKPI GILLLLWPTL WGLWLAADGM PDPMILVIFV LGTILMRSAG
     CAINDFADRK IDPHVSRTRN RPLATGIISS REALLVAAGL SLCAFLLILP LNLLTILLSV
     PALLLAISYP FTKRFFAMPQ AYLGIAFSFG IPMAFAAQTG TVPPLAWLLV LANLFWVIAY
     DTEYALVDLA DDLKIGIKTS AITFGRFDVA GILLCHITFL SILTYAGILL QRGIWFYGAL
     LVALGLVIVQ YTMIRNREPA RCFQAFLHNN RVGAVIFAGI LLDTLI
//
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