ID Q0AVP3_SYNWW Unreviewed; 348 AA.
AC Q0AVP3;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Mannose-1-phosphate guanylyltransferase (GDP) {ECO:0000313|EMBL:ABI69211.1};
DE EC=2.7.7.22 {ECO:0000313|EMBL:ABI69211.1};
GN OrderedLocusNames=Swol_1914 {ECO:0000313|EMBL:ABI69211.1};
OS Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC Syntrophomonas.
OX NCBI_TaxID=335541 {ECO:0000313|EMBL:ABI69211.1, ECO:0000313|Proteomes:UP000001968};
RN [1] {ECO:0000313|Proteomes:UP000001968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2245B / Goettingen {ECO:0000313|Proteomes:UP000001968};
RX PubMed=21966920; DOI=10.1111/j.1462-2920.2010.02237.x;
RA Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L.,
RA McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.;
RT "The genome of Syntrophomonas wolfei: new insights into syntrophic
RT metabolism and biohydrogen production.";
RL Environ. Microbiol. 12:2289-2301(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000448; ABI69211.1; -; Genomic_DNA.
DR RefSeq; WP_011641304.1; NC_008346.1.
DR AlphaFoldDB; Q0AVP3; -.
DR STRING; 335541.Swol_1914; -.
DR KEGG; swo:Swol_1914; -.
DR eggNOG; COG0836; Bacteria.
DR HOGENOM; CLU_035527_0_1_9; -.
DR OrthoDB; 9806359at2; -.
DR Proteomes; UP000001968; Chromosome.
DR GO; GO:0008928; F:mannose-1-phosphate guanylyltransferase (GDP) activity; IEA:UniProtKB-EC.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0005976; P:polysaccharide metabolic process; IEA:InterPro.
DR CDD; cd02509; GDP-M1P_Guanylyltransferase; 1.
DR InterPro; IPR049577; GMPP_N.
DR InterPro; IPR001538; Man6P_isomerase-2_C.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR Pfam; PF01050; MannoseP_isomer; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ABI69211.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABI69211.1}.
FT DOMAIN 3..273
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT DOMAIN 308..344
FT /note="Mannose-6-phosphate isomerase type II C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01050"
SQ SEQUENCE 348 AA; 38772 MW; 8AB0E5C7A1DAC8A6 CRC64;
MIAVVLAGGK GLRLWPESRQ TRPKQLCKFV NGKSMLDHTI DRLMTAGSSR VIIITNDSLL
PGINELVQQR SDKEKIEILS EPEGKNTAPA VGLVLTRYYG EGEDEILGFF PADHHVLDTE
AFIDSVQRAC MAAQNGHLAT IGISPSRPET GYGYIEKTKW EIGEIPGVFS VNSFCEKPDP
ETANSYLASG SHMWNAGIYI SQAKTLCDQF KTHLPEIYEK LILGFDKYID SYPLLPEISL
DYGVAEKSDS MAVVPANFGW CDLGNWNALA EIYLPDLKNN VCNGNDVLLI DSNNCIIKQT
EKTIVLFGVD NLLLVESEDL VLVADRNRAQ DIREIVEFLQ EKKRFDLL
//
