ID Q0BW88_GRABC Unreviewed; 328 AA.
AC Q0BW88;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Quinone oxidoreductase, NADPH-dependent {ECO:0000313|EMBL:ABI60914.1};
DE EC=1.6.5.5 {ECO:0000313|EMBL:ABI60914.1};
GN OrderedLocusNames=GbCGDNIH1_0016 {ECO:0000313|EMBL:ABI60914.1};
OS Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Granulibacter.
OX NCBI_TaxID=391165 {ECO:0000313|EMBL:ABI60914.1, ECO:0000313|Proteomes:UP000001963};
RN [1] {ECO:0000313|EMBL:ABI60914.1, ECO:0000313|Proteomes:UP000001963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1260 / CGDNIH1 {ECO:0000313|Proteomes:UP000001963};
RX PubMed=17827295; DOI=10.1128/JB.00793-07;
RA Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E.,
RA Kupko J.J.III., Barbian K.D., Babar A., Dorward D.W., Holland S.M.;
RT "Genome sequence analysis of the emerging human pathogenic acetic acid
RT bacterium Granulibacter bethesdensis.";
RL J. Bacteriol. 189:8727-8736(2007).
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DR EMBL; CP000394; ABI60914.1; -; Genomic_DNA.
DR RefSeq; WP_011630724.1; NC_008343.2.
DR AlphaFoldDB; Q0BW88; -.
DR STRING; 391165.GbCGDNIH1_0016; -.
DR KEGG; gbe:GbCGDNIH1_0016; -.
DR eggNOG; COG0604; Bacteria.
DR HOGENOM; CLU_026673_3_1_5; -.
DR OrthoDB; 9805883at2; -.
DR Proteomes; UP000001963; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003960; F:NADPH:quinone reductase activity; IEA:UniProtKB-EC.
DR CDD; cd05286; QOR2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047618; QOR-like.
DR PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR PANTHER; PTHR48106:SF13; QUINONE OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ABI60914.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001963};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..326
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 328 AA; 34454 MW; 795684D1B50DFE60 CRC64;
MTKAIRMHAH GGPDVLSWED VPTPVPGPGE AVIRHAAVGL NFIDIYFRSG LYKAPSLPTV
LGMEGAGTVI EIGAGVTDIQ VGDRVAYATG PLGAYATERT IAADRLVKLP DSISCQTAAA
MMLQGLTAQY LLRRTYPVKR GDTILVYAAA GGVGLILCQW AAYLGASVIG VVSTEEKAAL
ARAHGASHVI VSSNDHPADI AGEVRRITQG AMVPVVYDSV GKDTFDASLD CLAPLGLMVS
YGNASGPVPP FSLTTLSAKG SLFVTRPSLA TYTAKRADLL AMAQDLFDVV STGHVHIEIN
QTYPLQQAAE AQRALEERRT TGSTILIP
//
