ID Q0CQI4_ASPTN Unreviewed; 617 AA.
AC Q0CQI4;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 03-MAY-2023, entry version 54.
DE RecName: Full=Polycystin cation channel PKD1/PKD2 domain-containing protein {ECO:0000259|Pfam:PF08016};
GN ORFNames=ATEG_04050 {ECO:0000313|EMBL:EAU35852.1};
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU35852.1, ECO:0000313|Proteomes:UP000007963};
RN [1] {ECO:0000313|Proteomes:UP000007963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CH476598; EAU35852.1; -; Genomic_DNA.
DR RefSeq; XP_001213228.1; XM_001213228.1.
DR AlphaFoldDB; Q0CQI4; -.
DR STRING; 341663.Q0CQI4; -.
DR EnsemblFungi; EAU35852; EAU35852; ATEG_04050.
DR GeneID; 4318168; -.
DR VEuPathDB; FungiDB:ATEG_04050; -.
DR eggNOG; ENOG502QTER; Eukaryota.
DR HOGENOM; CLU_014123_0_0_1; -.
DR OMA; YQKCIKY; -.
DR OrthoDB; 1387259at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR013122; PKD1_2_channel.
DR PANTHER; PTHR35859; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR PANTHER; PTHR35859:SF1; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR Pfam; PF08016; PKD_channel; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007963};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 245..442
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
FT COILED 571..598
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 617 AA; 71333 MW; 22E227596AB0697C CRC64;
MERHRLLPAY AADNIPASHP AKEVTKVALR LKYQIEQVIS CELDESIITD PNSKIITNAV
VQTAKAAGGD DLRGCILFGL LVCLRWFKIQ AIEELWDSDL HERRALACEV IAKKIIETEE
DHDFLLVNCL LKRYSIFVDG EETHPANVIE RAVDLHALRI IGSSGYQKCI RYLWNGWFCQ
EDGNPTNFVP YHDKDNTSFA VHFHPDRMRT PQYQNACQIF FSLVYLILYT QVINTVNRTG
DLDFVEGILY VMTLGFICDE LSKLWKIGRH YFDFWNAFNS TLYALLAVSF FLRIAALTHS
PSAGDEKRQR LNEMSYNFLA FSGPMFWMRM MLYLDSFRFF GAMFVVLRVM MKESLIFFAL
LFVVLVGFFQ AFFGMAQFEP EIPITRVIVQ GMANSVMQSP EFSTFEEFAF PFGIILYYIF
NFIVMTILLN ILIALYNSAY EDIAGNSTDE YMAIFAQKTM QFVRAPDENV FIPPFNLIEI
LFLIIPFEWW LPRRHYAKLN DIVMGVLYSP LLLVTAALEV REARRIRWNR RRGEEDDDDV
QEWEHIAEEV DFEVDDSWKQ AVQETTPDIN ANSATHEIIK LRAQIDSLAE MVRLLTDEKL
VTGGFNGESS STIAERE
//
