ID   Q0K532_CUPNH            Unreviewed;       306 AA.
AC   Q0K532;
DT   03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Transcriptional regulator, LysR-family {ECO:0000313|EMBL:CAJ94892.1};
GN   OrderedLocusNames=H16_B0086 {ECO:0000313|EMBL:CAJ94892.1};
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ94892.1, ECO:0000313|Proteomes:UP000008210};
RN   [1] {ECO:0000313|EMBL:CAJ94892.1, ECO:0000313|Proteomes:UP000008210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC   337 {ECO:0000313|Proteomes:UP000008210};
RX   PubMed=16964242; DOI=10.1038/nbt1244;
RA   Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA   Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA   Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT   "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT   eutropha H16.";
RL   Nat. Biotechnol. 24:1257-1262(2006).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
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DR   EMBL; AM260480; CAJ94892.1; -; Genomic_DNA.
DR   RefSeq; WP_010814067.1; NZ_CP039288.1.
DR   AlphaFoldDB; Q0K532; -.
DR   STRING; 381666.H16_B0086; -.
DR   GeneID; 57645965; -.
DR   KEGG; reh:H16_B0086; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_4_4; -.
DR   OrthoDB; 5292387at2; -.
DR   Proteomes; UP000008210; Chromosome 2.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08448; PBP2_LTTR_aromatics_like_2; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008210}.
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   306 AA;  33344 MW;  C0EF676CEEFC810A CRC64;
     MEFRHLRYFL VLAEELHFGR AARRLAISQP PLSLNIQQLE ASVGARLFDR DSRGVRLTAA
     GRAFRESATA LLAQAEAARV LAREIEAGAI GRLRVGFVGS MLYRGLPQTL RAFQAAYPGI
     QVALTELNSQ EQIDALLHDE LDVAFIHTGR VPDTLQATLV HSEPFVCCLP ADHALAALPE
     LPLAALRGKP FVLFSRKASP DYYSRIFDMC AAQGFYPQIR HEVRHWLSVV SLVSQGMGVA
     VVPAALARSG MAGAAFRPLA DASVRSEVYC AWKTAPDHPA RDHFVGMVRE MTAAAHGSPK
     EKATGP
//