ID Q0KB81_CUPNH Unreviewed; 547 AA.
AC Q0KB81;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|SMART:SM00327};
GN OrderedLocusNames=H16_A1608 {ECO:0000313|EMBL:CAJ92740.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ92740.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ92740.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
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DR EMBL; AM260479; CAJ92740.1; -; Genomic_DNA.
DR RefSeq; WP_011615183.1; NC_008313.1.
DR AlphaFoldDB; Q0KB81; -.
DR STRING; 381666.H16_A1608; -.
DR KEGG; reh:H16_A1608; -.
DR PATRIC; fig|381666.6.peg.1993; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG2304; Bacteria.
DR HOGENOM; CLU_024570_3_2_4; -.
DR OrthoDB; 9807628at2; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR PANTHER; PTHR22550:SF14; VWFA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00028; TPR; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008210};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 96..261
FT /note="VWFA"
FT /evidence="ECO:0000259|SMART:SM00327"
FT REPEAT 419..452
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 469..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 60839 MW; 103BC386769146AE CRC64;
MQALDTLAHF HFLRPWWLLV LVPAALLVWA VQRRGDVRRR WRQTIAPHLL DALVIGERRR
VALRPVHLTA LLLALGAIAL AGPSWRQERP PFLDDKAPLA IAVDLSRTMD AVDVTPTRLE
RAKLKIKALL ARRGGGRTAI YAYAGSTHLV LPLTDDTNLL QTFVDALQTR IMPVPGRDMA
QALRTIDADL AREPVPGTIL FLTDGVDPAA GRAFRAQADS GRSQPVVLAI GTEQGGPLRN
AAGGYVEQDG ARVFARLDVA AFKRFGDDSG TPLATFTPGS DDDVAWVQRH VQSHLEQMQA
GDRTRWKDEG WWLVLPVTLL AMLWFRKGWT VRWTAGLLLA LAFAAPQPGL RAQQADGARP
WRFADLWLTH DQQGRRAFEQ GDFARAATLF DDAMWRGIAQ YRAGQYAQAV QSFALVDSPQ
ADYNQGNALA RQGQYQQAAA RYRQALRRQP QWPAATANLA LMEKLLAQQK PKDKPDPDDQ
EEPPDVPPDE IKYDAAKPPE QGGQSMHIGL TQDAEMWMRA IRTTPTDLLQ RKFALQRGQA
APQQGQR
//
