ID Q0KD08_CUPNH Unreviewed; 478 AA.
AC Q0KD08;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Transcriptional regulator, MocR family {ECO:0000313|EMBL:CAJ92113.1};
DE EC=2.6.1.- {ECO:0000313|EMBL:CAJ92113.1};
GN OrderedLocusNames=H16_A0970 {ECO:0000313|EMBL:CAJ92113.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ92113.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ92113.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; AM260479; CAJ92113.1; -; Genomic_DNA.
DR RefSeq; WP_010809211.1; NZ_CP039287.1.
DR AlphaFoldDB; Q0KD08; -.
DR STRING; 381666.H16_A0970; -.
DR GeneID; 57643071; -.
DR KEGG; reh:H16_A0970; -.
DR PATRIC; fig|381666.6.peg.1346; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_0_4; -.
DR OrthoDB; 9804020at2; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:CAJ92113.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000008210};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:CAJ92113.1}.
FT DOMAIN 4..72
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 478 AA; 51281 MW; FB9D6DFE45F5834F CRC64;
MESAPLYRQV AGHYRRAIES GTLAAGDRMP SVRALMALHS VSLSTALQAC RQLESDGLLE
ARPRSGYFVA APLRSPLAAL AEPAAALPDP AQYVGIHQRI SGLLARGQHQ HVHTNLGGAY
CAPSLYPTEA LRSAATRALR RHPMLFGEAV EPEGYQPLRS ALARQALRAR VQLAPEEIVI
TNGCTEALNL ALRAVAGPGD VIAVESPTYY GLLQILESLG MRALEIPCSP QTGISLEALE
LAAQHYDNIR AVAVVPNLQN PLGCIMPDAH KARLVQWCEA RGIALIEDDC FSATADSDAP
PAAAKAWDGS GNVIHCASLH KVLAPGMRLG WIAAGKWQAR VEMLKFGLSR PNEMLSQMAA
ADFLASGAHD RHLRRLRTRL CAQREWFAQA IAASFPAGTR LGSPRGGMHL WVELPAQISS
EAVFDQALQA GIRVMPGVMF SNAGRFDHCL RVNCGTPRSA QIERALGTLA AIVQRLAG
//
