ID Q0KEQ6_CUPNH Unreviewed; 515 AA.
AC Q0KEQ6;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Predicted Zn-dependent peptidase, M16B subfamily {ECO:0000313|EMBL:CAJ91515.1};
DE EC=3.4.-.- {ECO:0000313|EMBL:CAJ91515.1};
GN OrderedLocusNames=H16_A0364 {ECO:0000313|EMBL:CAJ91515.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ91515.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ91515.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM260479; CAJ91515.1; -; Genomic_DNA.
DR RefSeq; WP_010814799.1; NZ_CP039287.1.
DR AlphaFoldDB; Q0KEQ6; -.
DR STRING; 381666.H16_A0364; -.
DR MEROPS; M16.019; -.
DR GeneID; 57642460; -.
DR KEGG; reh:H16_A0364; -.
DR PATRIC; fig|381666.6.peg.728; -.
DR eggNOG; COG0612; Bacteria.
DR HOGENOM; CLU_009902_1_0_4; -.
DR OrthoDB; 9811314at2; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CAJ91515.1};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000008210};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 96..240
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 250..430
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT REGION 496..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 57504 MW; 0BA328AA43E9634C CRC64;
MNHCAVLAAA GAQGTKACVA TRFQRLSPSS KPLPARAARL ARRVIPTLLL ALLPWSMPAG
AQGVVASPMP GTQTAPAGAT AHGTTEYRLS NGLRLIVKED HRAPTVAHQI WYRVGGIDEV
SGTTGVAHML EHMMFKGTPK VGVGEFSKQV AALGGRENAM TNRDFTMYYQ QIGKQYLPRM
MELEADRMAN LVITKDEFER EMKVVMEERR LRTDDSARGT VYEQLLATVY TAAAYRHPVI
GWMDDLVNMR VDDVKEWYRH WYVPNNAMVI VTGDVKAEEV RALAERYYGK LKPRTLPLRK
DQEEPAQKGI KRIWVKAPAE NQYMVMAYKV PRLRDIEKDV DPYALEVLAA VLNGYDNARL
TRELVREQRL ADDVNVGYDS INRGESLFVL DGTPATGHNT DEIERALRAE VQRIAKEGVS
PEELKRVKAQ VVAGQIYKRD SVFGQGMEIG VSEISDISWR QIDRMLDKIK AVTPAQVQAV
AAKYFNDDNL TVATLVPQPI DPNKPKSQAP SGLRH
//
