ID Q0RPL7_FRAAA Unreviewed; 498 AA.
AC Q0RPL7;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=dolichyl-phosphate beta-glucosyltransferase {ECO:0000256|ARBA:ARBA00012583};
DE EC=2.4.1.117 {ECO:0000256|ARBA:ARBA00012583};
GN OrderedLocusNames=FRAAL1864 {ECO:0000313|EMBL:CAJ60514.1};
OS Frankia alni (strain DSM 45986 / CECT 9034 / ACN14a).
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=326424 {ECO:0000313|EMBL:CAJ60514.1, ECO:0000313|Proteomes:UP000000657};
RN [1] {ECO:0000313|EMBL:CAJ60514.1, ECO:0000313|Proteomes:UP000000657}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACN14a {ECO:0000313|Proteomes:UP000000657};
RX PubMed=17151343; DOI=10.1101/gr.5798407;
RA Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA Benson D.R.;
RT "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT reflect host range and host plant biogeography.";
RL Genome Res. 17:7-15(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a dolichyl phosphate + UDP-alpha-D-glucose = a dolichyl beta-
CC D-glucosyl phosphate + UDP; Xref=Rhea:RHEA:15401, Rhea:RHEA-
CC COMP:9517, Rhea:RHEA-COMP:9528, ChEBI:CHEBI:57525, ChEBI:CHEBI:57683,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.117;
CC Evidence={ECO:0000256|ARBA:ARBA00034053};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
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DR EMBL; CT573213; CAJ60514.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0RPL7; -.
DR STRING; 326424.FRAAL1864; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR KEGG; fal:FRAAL1864; -.
DR eggNOG; COG0463; Bacteria.
DR HOGENOM; CLU_547197_0_0_11; -.
DR OrthoDB; 2369748at2; -.
DR Proteomes; UP000000657; Chromosome.
DR GO; GO:0004581; F:dolichyl-phosphate beta-glucosyltransferase activity; IEA:RHEA.
DR CDD; cd04188; DPG_synthase; 1.
DR InterPro; IPR035518; DPG_synthase.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR10859:SF91; DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR10859; GLYCOSYL TRANSFERASE; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:CAJ60514.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000657};
KW Transferase {ECO:0000313|EMBL:CAJ60514.1}.
FT DOMAIN 7..162
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
FT REGION 264..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 50330 MW; 37C10EDA98628C95 CRC64;
MDSVPVSVII PAYNEAMRLP GLLAELVSVM RKIPDAEVIL VDDGSTDGTA AVAEGYLAEV
PGGRVLRLPW NSGKGAAVRA GVSVAHGASI VFMDADGASD VNDLPLLLAA LEHAEVALGS
RRIGAGAVRS SGRRVGSWAF NQITRSLASL DVADTQCGFK AFRGQEAKLL FSLARSTGFG
FDVEVLSIAR SIGYRIAEVP IHWAEIPGGT FRVTRHTPAM IVDVVRARRY LGRAAPGLVV
PANPVSTVQP VPTVQPVRPE SAVQLGAAGQ SHSPAQPATA AQPASAVPPV SRDPAVSRGP
SVPSDSSAAP ARGGAARRGA PAARPDRADG LGRPVVGAVA RGPLSPPRRP RPETVQPAAA
RRGDPPAGVA GSDRSAADRS PADRSPADRS PADPVVLGSA AEPAGAGRTS DAGGAALVLP
SATMSLPSAG VSRLAGSRVA LAHPGETVEE PVVTIPTPGG EPTTAATAAL AAVLATTVGR
GELSVRPAPE RDGAARSS
//
