ID Q0RTK0_FRAAA Unreviewed; 756 AA.
AC Q0RTK0;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Putative integral membrane export protein {ECO:0000313|EMBL:CAJ59098.1};
GN OrderedLocusNames=FRAAL0423 {ECO:0000313|EMBL:CAJ59098.1};
OS Frankia alni (strain DSM 45986 / CECT 9034 / ACN14a).
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=326424 {ECO:0000313|EMBL:CAJ59098.1, ECO:0000313|Proteomes:UP000000657};
RN [1] {ECO:0000313|EMBL:CAJ59098.1, ECO:0000313|Proteomes:UP000000657}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACN14a {ECO:0000313|Proteomes:UP000000657};
RX PubMed=17151343; DOI=10.1101/gr.5798407;
RA Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA Benson D.R.;
RT "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT reflect host range and host plant biogeography.";
RL Genome Res. 17:7-15(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CT573213; CAJ59098.1; -; Genomic_DNA.
DR RefSeq; WP_011601679.1; NC_008278.1.
DR AlphaFoldDB; Q0RTK0; -.
DR STRING; 326424.FRAAL0423; -.
DR KEGG; fal:FRAAL0423; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_1_1_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000000657; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000657};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 561..582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 214..339
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 733..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..756
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 80162 MW; 9AE9432E3F9CB8E8 CRC64;
MKRIAELAVR RRWLVVVGWV VFVIAAQGIA GAMGGASYKD TFSLPHTETA SVANLLEDAG
LNNQNGALGT VVLKNRAGAF TTPPAQLKPA LSKVCTSGNH VALIVSPWES IDCSKSDAAA
PGNPGLLNRA HGSTTALVTL TWENDHYDAE LFKNVYDQLK TLRSDALQVE FTGNAFAGIG
QSSGSGSSVF IGFAAALIIL ALVFRTVAAT VLPLASAVVA LVSGLGVIYI LSHAINVSNI
TPYLAELMVI GVGVDYALFI VTRHRRNLRR GMPVAESIVN AINTSGRAVL FAGTTVCIAI
LGLIALGVSF FNGMAVATAL AVGFTMIASL TLLPALLSLF GLKVLPRRQR AAVRAGEFID
DRPVGYWARW SQFVARRRVV VAIASGAVMV VIALPFFSLE LGASDQGSDA KSFTTRAGYD
LIAADFGVGY NSTLEAVVSG PGASDQAYLQ RVTKSLAAVP GVDPASLGTA PLAKDIAFVT
FKTTTSPQSE KTYTLVRHLR STTLPPLYDG TPNHIYTFGD TAINVDFASV LARKMPLFIA
VVVGLSFILL LIAFRSLVIP LTAAVMNLLA AGGSFGLVVA IFQYGWLSDA MGAGPGGPID
AWIPVMLFAI LFGLSMDYQV FLVSRMHEEW VHTRDNTRSV TIGQGETGGI ITAAAIIMIA
VFLGFVVSPG RPIKIFGTGL AAAVFLDAFV LRTMLVPSVM HIVGRSNWYL PRWLDRITPH
VSVEPADEAV THATGTGIGS FDDDRPEDER ELAHRS
//
