ID Q0S7R9_RHOJR Unreviewed; 209 AA.
AC Q0S7R9;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 128.
DE SubName: Full=Probable transcriptional regulator, TetR family protein {ECO:0000313|EMBL:ABG96417.1};
GN OrderedLocusNames=RHA1_ro04631 {ECO:0000313|EMBL:ABG96417.1};
OS Rhodococcus jostii (strain RHA1).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=101510 {ECO:0000313|EMBL:ABG96417.1, ECO:0000313|Proteomes:UP000008710};
RN [1] {ECO:0000313|Proteomes:UP000008710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RHA1 {ECO:0000313|Proteomes:UP000008710};
RX PubMed=17030794; DOI=10.1073/pnas.0607048103;
RA McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C.,
RA Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H.,
RA Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H.,
RA Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R.,
RA Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W.,
RA Eltis L.D.;
RT "The complete genome of Rhodococcus sp. RHA1 provides insights into a
RT catabolic powerhouse.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006).
RN [2] {ECO:0007829|PDB:2GFN}
RP X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 2-209.
RA Nocek B., Evdokimova E., Kagan O., Savchenko A., Edwards A., Joachimiak A.;
RT "Crystal structure of HTH-type transcriptional regulator pksA related
RT protein from Rhodococcus sp. RHA1.";
RL Submitted (MAR-2006) to the PDB data bank.
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DR EMBL; CP000431; ABG96417.1; -; Genomic_DNA.
DR PDB; 2GFN; X-ray; 1.90 A; A/B=1-209.
DR PDBsum; 2GFN; -.
DR AlphaFoldDB; Q0S7R9; -.
DR SMR; Q0S7R9; -.
DR KEGG; rha:RHA1_ro04631; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_15_10_11; -.
DR EvolutionaryTrace; Q0S7R9; -.
DR Proteomes; UP000008710; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR47506:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATOR YJDC; 1.
DR PANTHER; PTHR47506; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:2GFN};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000008710};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..68
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 31..50
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 209 AA; 22510 MW; 5EC8EAE25558D5D3 CRC64;
MPKIVDHDER RRALADAVLA LIAREGISAV TTRAVAEESG WSTGVLNHYF GSRHELLLAA
LRRAGDIQGD RYRTILDEEG AGPIEKLRNI TASILPLDER RLAMTRVFLF FYAEGAAEET
ARGEIAAFLA RWRGVVRESV VAAQREGTVS TDLDADAVTV ALVALTDGLA LQAILDPVVM
KAISAEDAAA RCVDAAVRRT TEEAGAVGR
//
