ID   Q0U6K3_PHANO            Unreviewed;       697 AA.
AC   Q0U6K3;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 2.
DT   24-JAN-2024, entry version 97.
DE   RecName: Full=Peptidase M3A/M3B catalytic domain-containing protein {ECO:0000259|Pfam:PF01432};
GN   ORFNames=SNOG_12611 {ECO:0000313|EMBL:EAT79909.2};
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614 {ECO:0000313|EMBL:EAT79909.2, ECO:0000313|Proteomes:UP000001055};
RN   [1] {ECO:0000313|Proteomes:UP000001055}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173
RC   {ECO:0000313|Proteomes:UP000001055};
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G., Solomon P.S., Tan K.C., Schoch C.L., Spatafora J.W.,
RA   Crous P.W., Kodira C., Birren B.W., Galagan J.E., Torriani S.F.,
RA   McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU003435};
CC       Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC   -!- SIMILARITY: Belongs to the peptidase M3 family.
CC       {ECO:0000256|ARBA:ARBA00006040, ECO:0000256|RuleBase:RU003435}.
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DR   EMBL; CH445347; EAT79909.2; -; Genomic_DNA.
DR   RefSeq; XP_001802832.1; XM_001802780.1.
DR   AlphaFoldDB; Q0U6K3; -.
DR   STRING; 321614.Q0U6K3; -.
DR   MEROPS; M03.009; -.
DR   EnsemblFungi; SNOT_12611; SNOT_12611; SNOG_12611.
DR   GeneID; 5979743; -.
DR   KEGG; pno:SNOG_12611; -.
DR   VEuPathDB; FungiDB:JI435_126110; -.
DR   eggNOG; KOG2089; Eukaryota.
DR   HOGENOM; CLU_001805_1_1_1; -.
DR   InParanoid; Q0U6K3; -.
DR   OrthoDB; 735202at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IBA:GO_Central.
DR   GO; GO:0006518; P:peptide metabolic process; IBA:GO_Central.
DR   GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR   CDD; cd06455; M3A_TOP; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   Gene3D; 1.10.1370.10; Neurolysin, domain 3; 1.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR024077; Neurolysin/TOP_dom2.
DR   InterPro; IPR024080; Neurolysin/TOP_N.
DR   InterPro; IPR045090; Pept_M3A_M3B.
DR   InterPro; IPR001567; Pept_M3A_M3B_dom.
DR   PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR   PANTHER; PTHR11804:SF84; SACCHAROLYSIN; 1.
DR   Pfam; PF01432; Peptidase_M3; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU003435};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU003435};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001055};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT   DOMAIN          194..694
FT                   /note="Peptidase M3A/M3B catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01432"
SQ   SEQUENCE   697 AA;  79553 MW;  9B4887CA60534643 CRC64;
     MAQIDRSRGI QDAIVRDVKP DTASFANVIL PIAHDDNKMA IESHIIGFYN AVSTDKELRD
     ASSEAEQLLD DFGIESSMRE DVFNLVDAAL KKKEQLDPES QRLLEKDHKS YIRNGLSLPA
     GPKRDRFKEI KQRLSQISIA FQKNLNEENG ELWFTPEELH GVPEDVIATL NKGEGDKEGK
     LRLTFKYPDL FPTLKYATNA ETRKTVMTAN ENKCNDNVAL FREAILLRDE AARILGYENH
     AQFRIEDKMA KTPKTVNDFL ADLRKRLAPG GKKEIEKLME FKKQDVKEQG LTGPLAEGYY
     LWDHRYYDRL MLEKDYQLDH QVIAEYFPLQ TTIQGMLKIF EELFGLVFVE IVGEKDRAAL
     AEGGKGSDIV WHKDVSIFSV WDDEGEGAGF VGYLYLDLFP RDGKYGHAAN FNLQPGYIDE
     NGKRRYPATA LVCNFSKPTP KKPSLLKHDE VVTLFHELGH GIHDLVSRTT YARFHGTSTV
     RDFVEAPSQM LENWCWTPSQ LRSLSHHYSY LSPEYEKAYI ESSGLEKKPS EQIPNSLIAN
     LINTKHVNDA LFNLRQLHFG TFDMTVHQPA SHEELKKLDI TETYNKLRNE ISQLNGPEAL
     DGPTKGDWHW GNGQATFGHL IGGYDAGYYG YLSSQVYSTD MFYTVFKADP MNGKEGRRYR
     HTVLERGGSK EEMEILEEFL GRKPETEAFY KELGIGQ
//