ID Q0UU18_PHANO Unreviewed; 988 AA.
AC Q0UU18;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 2.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=116 kDa U5 small nuclear ribonucleoprotein component {ECO:0000256|ARBA:ARBA00018774};
DE AltName: Full=U5 snRNP-specific protein, 116 kDa {ECO:0000256|ARBA:ARBA00031432};
GN ORFNames=SNOG_04746 {ECO:0000313|EMBL:EAT88506.2};
OS Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS blotch fungus) (Parastagonospora nodorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC Parastagonospora.
OX NCBI_TaxID=321614 {ECO:0000313|EMBL:EAT88506.2, ECO:0000313|Proteomes:UP000001055};
RN [1] {ECO:0000313|Proteomes:UP000001055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173
RC {ECO:0000313|Proteomes:UP000001055};
RX PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA Hane J.K., Lowe R.G., Solomon P.S., Tan K.C., Schoch C.L., Spatafora J.W.,
RA Crous P.W., Kodira C., Birren B.W., Galagan J.E., Torriani S.F.,
RA McDonald B.A., Oliver R.P.;
RT "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT analysis of the wheat pathogen Stagonospora nodorum.";
RL Plant Cell 19:3347-3368(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CH445330; EAT88506.2; -; Genomic_DNA.
DR RefSeq; XP_001795158.1; XM_001795106.1.
DR AlphaFoldDB; Q0UU18; -.
DR STRING; 321614.Q0UU18; -.
DR EnsemblFungi; SNOT_04746; SNOT_04746; SNOG_04746.
DR GeneID; 5972026; -.
DR KEGG; pno:SNOG_04746; -.
DR VEuPathDB; FungiDB:JI435_047460; -.
DR eggNOG; KOG0468; Eukaryota.
DR HOGENOM; CLU_002794_11_2_1; -.
DR InParanoid; Q0UU18; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000001055; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0071014; C:post-mRNA release spliceosomal complex; IEA:EnsemblFungi.
DR GO; GO:0000974; C:Prp19 complex; IEA:EnsemblFungi.
DR GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR GO; GO:0005682; C:U5 snRNP; IEA:EnsemblFungi.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0030623; F:U5 snRNA binding; IBA:GO_Central.
DR GO; GO:0000349; P:generation of catalytic spliceosome for first transesterification step; IEA:EnsemblFungi.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IEA:EnsemblFungi.
DR GO; GO:0000388; P:spliceosome conformational change to release U4 (or U4atac) and U1 (or U11); IEA:EnsemblFungi.
DR CDD; cd04098; eEF2_C_snRNP; 1.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR035655; U5-116kDa_C.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001055};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 129..339
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 988 AA; 110790 MW; F8DBF40AA5140C51 CRC64;
MDDLYDEFGN FIGEAESDED DQTNGEAADA YVLDDEEQEE AEVNDQQLME IDDGPSNAVV
LHEDKQYYPS ASDVYGPDVE ILVQEEDTQS LAQPIIAPVV QKKFIAQETD LPPVYHSREL
LTDLMNFPNQ IRNIAIAGHL HHGKTAFMDM LVMETHDIQD RLDYKKGKKR EEQLRYTDVH
VLERERGLSI KAAPMSLVLQ NTKSKSHLFN ILDTPGHVNF ADEVAASLRL VDGVVLVVDV
VEGVQVNTEQ IIKHAVLEDL PLTLVVNKMD RLIFDAYFKI KHVIVQVNTV IEDTIPGRGE
SRRVSPEKGN VAFACSSMRW SFTIQSFAKM YSDFYPGPSK LPGFGVPMKG LDIEKFAMRL
WGDIYYNPGS RKFSRKRQEE GAQRSFVHWI LEPVYKLYSH TLSESSADLK DTLDALGIRL
KPSEYKTDAK ELMRLVCQQY FGPSMGFVDM ITQHVPSPAE GAKRLLQRHY TGPLDTKTAE
AMEKCDQDGP LVVHVTKLFN ATDAKSFTAL GRVMSGIAKS PQSVRVLGEG YTLEDEEDMV
VATVTDTWIA ESRYNIPVSG VPAGNWVLLG GVDNSIVKTA TIVASKLPDD EDAYIFRPIR
HFFESVFKVA VEPINPSELP KMLDGLRKIN KSYPLITTKV EESGEHVVLG TGELYMDCVL
HDLRRLYADM EIKVSDPVTR FSETVVEMSA IKCYAMTPNK KNKLTMIAEP LDPGIAEDIE
AGKVNIKDPV RVVGKFFEEN YGYDLLASRN IWAFGPDEMG PNILQNDTLP SEVDTKTLRT
VRDTLRQGFS WATREGPLCE EPIRNTKFRI TDVELAPEAI FRGGGQIIPT SRRACYSSFL
MASPRLMEPV YSCSMVGPAD TKSSLYTVLA RRRGHVLQDG PIAGTPLYNV RGLIPVIDSF
GFETDLRIHT QGQVSLSLVF DRWSIVPGDP LDKEIKLRPL DPATAQQLAR DFVLKTRRRK
GLAEDVTISK FLEPELFRSL KESGVLDG
//
