ID Q0VG47_MOUSE Unreviewed; 357 AA.
AC Q0VG47;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 138.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein A3 {ECO:0000313|EMBL:AAI57920.1};
DE SubName: Full=Hnrpa3 protein {ECO:0000313|EMBL:AAI16252.1};
GN Name=Hnrnpa3 {ECO:0000313|EMBL:AAI57920.1,
GN ECO:0000313|MGI:MGI:1917171};
GN Synonyms=Hnrpa3 {ECO:0000313|EMBL:AAI16252.1};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAI16252.1};
RN [1] {ECO:0000313|EMBL:AAI16252.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain {ECO:0000313|EMBL:AAI57920.1}, and PCR rescued clones
RC {ECO:0000313|EMBL:AAI16252.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; BC116250; AAI16251.1; -; mRNA.
DR EMBL; BC116251; AAI16252.1; -; mRNA.
DR EMBL; BC157919; AAI57920.1; -; mRNA.
DR EMBL; BC158038; AAI58039.1; -; mRNA.
DR RefSeq; NP_444493.1; NM_053263.1.
DR RefSeq; XP_011237818.1; XM_011239516.2.
DR SMR; Q0VG47; -.
DR TopDownProteomics; Q0VG47; -.
DR Antibodypedia; 19537; 157 antibodies from 23 providers.
DR DNASU; 229279; -.
DR GeneID; 229279; -.
DR UCSC; uc008kel.2; mouse.
DR AGR; MGI:1917171; -.
DR CTD; 220988; -.
DR MGI; MGI:1917171; Hnrnpa3.
DR VEuPathDB; HostDB:ENSMUSG00000059005; -.
DR HOGENOM; CLU_012062_1_0_1; -.
DR OrthoDB; 3127428at2759; -.
DR BioGRID-ORCS; 229279; 12 hits in 78 CRISPR screens.
DR ChiTaRS; Hnrnpa3; mouse.
DR ExpressionAtlas; Q0VG47; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12763; RRM1_hnRNPA3; 1.
DR CDD; cd12582; RRM2_hnRNPA3; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR034516; hnRNPA1/3_RRM2.
DR InterPro; IPR034513; hnRNPA3_RRM1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR48026:SF12; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3; 1.
DR PANTHER; PTHR48026; HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 2: Evidence at transcript level;
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000313|EMBL:AAI57920.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 13..96
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 104..183
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 182..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 37086 MW; 222DBB3DF00D2D7A CRC64;
MEGHDPKEPE QLRKLFIGGL SFETTDDSLR EHFEKWGTLT DCVVMRDPQT KRSRGFGFVT
YSCVEEVDAA MCARPHKVDG RVVEPKRAVS REDSVKPGAH LTVKKIFVGG IKEDTEEYNL
RDYFEKYGKI ETIEVMEDRQ SGKKRGFAFV TFDDHDTVDK IVVQKYHTIN GHNCEVKKAL
SKQEMQSAGS QRGRGGGSGN FMGRGGNFGG GGGNFGRGGN FGGRGGYGGG GGGSRGSYGG
GDGGYNGFGG DGGNYGGGPG YSSRGGYGGG GPGYGNQGGG YGGGGGGYDG YNEGGNFGGG
NYGGGGNYND FGNYSGQQQS NYGPMKGGSF GGRSSGSPYG GGYGSGGGSG GYGSRRF
//
