ID Q0VT02_ALCBS Unreviewed; 428 AA.
AC Q0VT02;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=ABC export system, membrane fusion protein {ECO:0000313|EMBL:CAL15696.1};
GN OrderedLocusNames=ABO_0248 {ECO:0000313|EMBL:CAL15696.1};
OS Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 /
OS SK2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Alcanivoracaceae; Alcanivorax.
OX NCBI_TaxID=393595 {ECO:0000313|EMBL:CAL15696.1, ECO:0000313|Proteomes:UP000008871};
RN [1] {ECO:0000313|EMBL:CAL15696.1, ECO:0000313|Proteomes:UP000008871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2
RC {ECO:0000313|Proteomes:UP000008871};
RX PubMed=16878126; DOI=10.1038/nbt1232;
RA Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M.,
RA Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C.,
RA Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B.,
RA McHardy A.C., Meyer F., Nechitaylo T., Puehler A., Regenhardt D., Rupp O.,
RA Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J.,
RA Weidner S., Kaiser O., Golyshin P.N.;
RT "Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium
RT Alcanivorax borkumensis.";
RL Nat. Biotechnol. 24:997-1004(2006).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AM286690; CAL15696.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0VT02; -.
DR STRING; 393595.ABO_0248; -.
DR KEGG; abo:ABO_0248; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_1_6; -.
DR Proteomes; UP000008871; Chromosome.
DR GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR GO; GO:1990195; C:macrolide transmembrane transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.1990; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR030190; MacA_alpha-hairpin_sf.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008871};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 104..338
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 145..179
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 428 AA; 47123 MW; 30A1A48E1169BCFB CRC64;
MAAWHSAVRA FNFELAISSL HISCNISRYI PHHHYWSVEL PMPRWIRRFP KTVLFVVVLI
VCLLFAGWRW GFSSAPATQW ETATVERGDV EELVTALGTL EPGDYVDVGA QVSGQLTHLY
VDVGDSVEEG QLLAEIDASV QQTQVDAGLA ELEALRAQLE QRQAELNLAE LQYQRQQRLR
DANATSEDAF QSAESNLAIT GAQIKVLQAQ IRQKQASVEG DQATLGYAKI YAPRSGTVVS
LDAREGQTLN ANQTTPTLMR IADLSVMTIS TEVSEADVHR LSAGMPVYFN TLGNETVRYD
SELRQVLPTP EVVNNVVLYT AEFDVANDNG QLMSGMTAQV FFVVNSARDV LSLPMAAVKR
AGRGAWKVQV LDSKGEPQDQ PVKIGIDNRV RIVIDEGLEE GDVVTLSQAS SNVALKKNKD
SLPRQGRF
//
