ID Q0W3U4_METAR Unreviewed; 395 AA.
AC Q0W3U4;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=Aminotransferase {ECO:0000256|RuleBase:RU000481};
DE EC=2.6.1.- {ECO:0000256|RuleBase:RU000481};
GN Name=aat-2 {ECO:0000313|EMBL:CAJ36949.1};
GN ORFNames=RCIX1738 {ECO:0000313|EMBL:CAJ36949.1};
OS Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanocellales; Methanocellaceae; Methanocella.
OX NCBI_TaxID=351160 {ECO:0000313|EMBL:CAJ36949.1, ECO:0000313|Proteomes:UP000000663};
RN [1] {ECO:0000313|EMBL:CAJ36949.1, ECO:0000313|Proteomes:UP000000663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22066 / NBRC 105507 / MRE50
RC {ECO:0000313|Proteomes:UP000000663};
RX PubMed=16857943; DOI=10.1126/science.1127062;
RA Erkel C., Kube M., Reinhardt R., Liesack W.;
RT "Genome of rice cluster I archaea -- the key methane producers in the rice
RT rhizosphere.";
RL Science 313:370-372(2006).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU000481};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|RuleBase:RU000481}.
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DR EMBL; AM114193; CAJ36949.1; -; Genomic_DNA.
DR RefSeq; WP_012035617.1; NC_009464.1.
DR AlphaFoldDB; Q0W3U4; -.
DR STRING; 351160.RCIX1738; -.
DR GeneID; 5143709; -.
DR KEGG; rci:RCIX1738; -.
DR eggNOG; arCOG01130; Archaea.
DR OrthoDB; 372018at2157; -.
DR Proteomes; UP000000663; Chromosome.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00609; AAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR004838; NHTrfase_class1_PyrdxlP-BS.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR46383:SF5; AMINOTRANSFERASE; 1.
DR PANTHER; PTHR46383; ASPARTATE AMINOTRANSFERASE; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00105; AA_TRANSFER_CLASS_1; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aminotransferase {ECO:0000256|RuleBase:RU000481,
KW ECO:0000313|EMBL:CAJ36949.1};
KW Histidine biosynthesis {ECO:0000256|ARBA:ARBA00023102};
KW Reference proteome {ECO:0000313|Proteomes:UP000000663};
KW Transferase {ECO:0000256|RuleBase:RU000481, ECO:0000313|EMBL:CAJ36949.1}.
FT DOMAIN 27..376
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
SQ SEQUENCE 395 AA; 44042 MW; 6C1DE6480BF0422B CRC64;
MKISNKVRNL PPSGIRKFFD IASGIPDAIS LGVGEPDFVT PWRVREASIY GLERGYTTYT
SNWGLLELRE QISKYIYDGA GVDYSPKNEV LVTTGVSEGI DLAVRAITDP GDEILVVEPS
YVSYKPCVIM AGGKPVVVNT TVDNDFRVTR EDLEAKITDR TTAIIMSYPN NPTGAIMPKK
YLEEVADVAI EHDLMVLSDE VYEKMTYEGT HTSIASLEGM RDNTILLNGF SKAFAMTGWR
LGFACGNPDV IEAMMKVHQY TMLCAPINAQ MAAIEALKSG QDDMQEMIKE YDRRRRVIVK
GFNDMGLDCF EPKGAFYAFP SIKKTGLTDT EFSERLVFEK HVIAVPGSVF GETGVGHLRC
SYATNMEQIK EALDRIAEFL QELEREQAPK IKTRT
//
