ID Q0WQA4_ARATH Unreviewed; 877 AA.
AC Q0WQA4;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=HAT dimerization domain-containing protein {ECO:0000313|EMBL:AEE75955.1};
GN OrderedLocusNames=At3g17450 {ECO:0000313|EMBL:AEE75955.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:BAF00695.1};
RN [1] {ECO:0000313|EMBL:AEE75955.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130713; DOI=10.1038/35048706;
RG European Union Chromosome 3 Arabidopsis Sequencing Consortium;
RG Institute for Genomic Research;
RG Kazusa DNA Research Institute;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Blocker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M.,
RA Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N.,
RA Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L.,
RA Weissenbach J., Saurin W., Quetier F., Schafer M., Muller-Auer S.,
RA Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N.,
RA Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P.,
RA Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S.,
RA Simionati B., Conrad A., Hornischer K., Kauer G., Lohnert T.H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schon O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwalder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.W., Mayer K.F., Kaul S.,
RA Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2] {ECO:0000313|EMBL:BAF00695.1}
RP NUCLEOTIDE SEQUENCE.
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Morosawa T.,
RA Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K.,
RA Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K.,
RA Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J.,
RA Hayashizaki Y., Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AEE75955.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AEE75955.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CP002686; AEE75955.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64974.1; -; Genomic_DNA.
DR EMBL; AK228799; BAF00695.1; -; mRNA.
DR RefSeq; NP_001326974.1; NM_001338290.1.
DR RefSeq; NP_188371.1; NM_112624.4.
DR AlphaFoldDB; Q0WQA4; -.
DR STRING; 3702.Q0WQA4; -.
DR PaxDb; 3702-AT3G17450-1; -.
DR ProteomicsDB; 175187; -.
DR EnsemblPlants; AT3G17450.1; AT3G17450.1; AT3G17450.
DR EnsemblPlants; AT3G17450.2; AT3G17450.2; AT3G17450.
DR GeneID; 821009; -.
DR Gramene; AT3G17450.1; AT3G17450.1; AT3G17450.
DR Gramene; AT3G17450.2; AT3G17450.2; AT3G17450.
DR KEGG; ath:AT3G17450; -.
DR TAIR; AT3G17450; -.
DR eggNOG; ENOG502QQE0; Eukaryota.
DR HOGENOM; CLU_016471_3_1_1; -.
DR OMA; PCKHAPE; -.
DR OrthoDB; 992745at2759; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q0WQA4; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR InterPro; IPR007021; DUF659.
DR InterPro; IPR008906; HATC_C_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR003656; Znf_BED.
DR PANTHER; PTHR32166:SF105; HAT DIMERIZATION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR32166; OSJNBA0013A04.12 PROTEIN; 1.
DR Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR Pfam; PF04937; DUF659; 1.
DR Pfam; PF02892; zf-BED; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50808; ZF_BED; 2.
PE 1: Evidence at protein level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q0WQA4,
KW ECO:0007829|ProteomicsDB:Q0WQA4};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00027}.
FT DOMAIN 8..64
FT /note="BED-type"
FT /evidence="ECO:0000259|PROSITE:PS50808"
FT DOMAIN 130..186
FT /note="BED-type"
FT /evidence="ECO:0000259|PROSITE:PS50808"
FT REGION 76..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 824..838
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..877
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 877 AA; 100526 MW; CAD90DD1988DD3E3 CRC64;
MAPPGSIGVV DPGWEHGVAQ DQRKKKVKCN YCGKIVSGGI YRLKQHLARV SGEVTYCDKS
PEEVCMRMKE NLVRSTKKLR QSEDNSGQSC SSFHQSNNDD EADEEERRCW SIRSKGKLGL
SDGSLLRSSG YIDPGWEHGI AQDERKKKVK CNYCNKIVSG GINRFKQHLA RIPGEVAPCK
TAPEEVYVKI KENMKWHRAG KRQNRPDDEM GALTFRTVSQ DPDQEEDRED HDFYPTSQDR
LMLGNGRFSK DKRKSFDSTN MRSVSEAKTK RARMIPFQSP SSSKQRKLYS SCSNRVVSRK
DVTSSISKFL HHVGVPTEAA NSLYFQKMIE LIGMYGEGFV VPSSQLFSGR LLQEEMSTIK
SYLREYRSSW VVTGCSIMAD TWTNTEGKKM ISFLVSCPRG VYFHSSIDAT DIVEDALSLF
KCLDKLVDDI GEENVVQVIT QNTAIFRSAG KLLEEKRKNL YWTPCAIHCT ELVLEDFSKL
EFVSECLEKA QRITRFIYNQ TWLLNLMKNE FTQGLDLLRP AVMRHASGFT TLQSLMDHKA
SLRGLFQSDG WILSQTAAKS EEGREVEKMV LSAVFWKKVQ YVLKSVDPVM QVIHMINDGG
DRLSMPYAYG YMCCAKMAIK SIHSDDARKY GPFWRVIEYR WNPLFHHPLY VAAYFFNPAY
KYRPDFMAQS EVVRGVNECI VRLEPDNTRR ITALMQIPDY TCAKADFGTD IAIGTRTELD
PSAWWQQHGI SCLELQRVAV RILSHTCSSV GCEPKWSVYD QVNSQCQSQF GKKSTKDLTY
VHYNLRLREK QLKQRLHYED EPPPTLNHAL LDRLLPDWLV TSEKEEEEAL HGEDRAEKED
HEDDEEEEEK FYMESGNVDG EGEDNLDPYD DDLSDDD
//
