ID Q0WXX3_CAVPO Unreviewed; 790 AA.
AC Q0WXX3;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 24-JAN-2024, entry version 98.
DE RecName: Full=Aryl hydrocarbon receptor nuclear translocator {ECO:0000256|ARBA:ARBA00039652};
GN Name=arnt {ECO:0000313|EMBL:BAF02596.1};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|EMBL:BAF02596.1};
RN [1] {ECO:0000313|EMBL:BAF02596.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Std:Hartley {ECO:0000313|EMBL:BAF02596.1};
RC TISSUE=Lung {ECO:0000313|EMBL:BAF02596.1};
RA Kawanishi M., Sakamoto M., Shimohara C., Yagi T.;
RT "aryl hydrocarbon receptor nuclear translocater, Arnt.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB263100; BAF02596.1; -; mRNA.
DR RefSeq; NP_001166569.1; NM_001173098.1.
DR AlphaFoldDB; Q0WXX3; -.
DR GeneID; 100379223; -.
DR KEGG; cpoc:100379223; -.
DR CTD; 405; -.
DR OrthoDB; 2872674at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd18947; bHLH-PAS_ARNT; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23042:SF50; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF88633; Positive stranded ssRNA viruses; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Receptor {ECO:0000313|EMBL:BAF02596.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 89..142
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 161..235
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 368..419
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..102
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 790 AA; 86633 MW; 9ACCAC348061A5DC CRC64;
MAATTANPEM TSDVPSLGPS IASGNPGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL
RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS
ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS
CETGRVVYVS DSVTPVLSQP QSEWFGSTLY DQVHPDDVDK LREQLSTSES ALTGRILDLK
TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG NSSVDPVSMN RLSFVRNRCR NGLGSVKDGE
PHFVVVHCTG YIKAWPPAGV SLPDDDPEAG QGSKFCLVAI GRLQVTSSPN CTDMSNVCQP
TEFISRHNIE GIFTFVDHRC VATVGYQPQE LLGKNIVEFC HPEDQQLLRD SFQQVVKLKG
QVLSVMFRFR SKTREWLWMR TSSFTFQNPY SDEIEYIICT NTNVKNSSQE PRPTLSNTVQ
RSQLGSTANL PLEMGSGQLA PRQQQQQTEL DMVSGRDGLA SYNHSQVSVQ PVASTGPEHS
KTLEKSDVLF AQDRDPRFSE IYSNINADQS KGISSSTVPA TQQLFSQGNS FPPNPRPAEN
FRNSGLAPSV TIVQPSSSAG QILAQISRHS NPSQGAAPTW TPSTRSGFSA QQVATQATAK
TRSSQFGVGN FQTPSSFSPM SLPGAPTASP GAATYPTLTN RGSNFAPEAG QTAGQFQTRT
AEGVGVWPQW QGQQPHHRSS SSEQHVQQPS AQQPSQPEVF QEMLSMLGDQ SNSYNNEEFP
DLAMFPPFSE
//
