ID Q0ZAS3_UREPR Unreviewed; 321 AA.
AC Q0ZAS3;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=6-phosphofructokinase {ECO:0000256|ARBA:ARBA00012055};
DE EC=2.7.1.11 {ECO:0000256|ARBA:ARBA00012055};
GN ORFNames=FJM04_00815 {ECO:0000313|EMBL:QDI64174.1};
OS Ureaplasma parvum (Ureaplasma urealyticum biotype 1).
OC Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae; Ureaplasma.
OX NCBI_TaxID=134821 {ECO:0000313|EMBL:ABG37047.1};
RN [1] {ECO:0000313|EMBL:ABG37047.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=1 {ECO:0000313|EMBL:ABG37047.1};
RA Momynaliev K.T., Klubin A.V., Chelysheva V.V., Selezneva O.V.,
RA Ladygina V.G., Akopian T.A., Govorun V.M.;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABG37047.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=1 {ECO:0000313|EMBL:ABG37047.1};
RX PubMed=17363224; DOI=10.1016/j.resmic.2007.01.002;
RA Momynaliev K., Klubin A., Chelysheva V., Selezneva O., Akopian T.,
RA Govorun V.;
RT "Comparative genome analysis of Ureaplasma parvum clinical isolates.";
RL Res. Microbiol. 158:371-378(2007).
RN [3] {ECO:0000313|EMBL:QDI64174.1, ECO:0000313|Proteomes:UP000316070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=106 {ECO:0000313|EMBL:QDI64174.1,
RC ECO:0000313|Proteomes:UP000316070};
RA Yang T., Zhang Y., Li X., Kong Y., Yu H., Ruan Z., Xie X., Zhang J.;
RT "Comparative genomics of three clinical Ureaplasma species: analysis of
RT their core genomes and virulence factors.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-
CC bisphosphate + H(+); Xref=Rhea:RHEA:16109, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:32966, ChEBI:CHEBI:57634,
CC ChEBI:CHEBI:456216; EC=2.7.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00000432};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 3/4.
CC {ECO:0000256|ARBA:ARBA00004679}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the phosphofructokinase type A (PFKA) family.
CC {ECO:0000256|ARBA:ARBA00038478}.
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DR EMBL; DQ648053; ABG37047.1; -; Genomic_DNA.
DR EMBL; CP041199; QDI64174.1; -; Genomic_DNA.
DR RefSeq; WP_006688917.1; NZ_JAHAKN010000002.1.
DR AlphaFoldDB; Q0ZAS3; -.
DR UniPathway; UPA00109; UER00182.
DR Proteomes; UP000316070; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.450; -; 1.
DR Gene3D; 3.40.50.460; Phosphofructokinase domain; 1.
DR InterPro; IPR022953; ATP_PFK.
DR InterPro; IPR012003; ATP_PFK_prok-type.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR InterPro; IPR035966; PKF_sf.
DR PANTHER; PTHR13697:SF4; ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE; 1.
DR PANTHER; PTHR13697; PHOSPHOFRUCTOKINASE; 1.
DR Pfam; PF00365; PFK; 1.
DR PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Phosphofructokinase; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABG37047.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 12..290
FT /note="Phosphofructokinase"
FT /evidence="ECO:0000259|Pfam:PF00365"
SQ SEQUENCE 321 AA; 36541 MW; BAAF648C3E1D5A6C CRC64;
MNQVNFLNLD KNILIITSGG DAPGMNASLI SLIHRLMNNN FNVFIGIEGL LGLYNNLIEP
IKDKRVFDVY FNEQGTVIKT SRFIKLDIND KKTQIIKDNL LSHNIQKIII LGGQGSMQAG
LVLTKMGFEV FGILHTIDND FSETQMCIGA LSAASFNQKL LKCLNYTAKA HCAFNLVELM
GRECSWLVNN SVGKLKPILM LTNQDNKYTV DEVIDLIKNK INSIKEYDPL IIVQELIYDQ
KWYELLVKTF EQKLHKSLRI TILNYLQRGA PVSDFDLQLA KDSANVLVDF IVNQNDIKNT
NNMYVVINKF DNKLEVIKFN K
//
