ID Q10GE4_ORYSJ Unreviewed; 1090 AA.
AC Q10GE4;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN OrderedLocusNames=LOC_Os03g43250 {ECO:0000313|EMBL:ABF97758.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000313|EMBL:ABF97758.1};
RN [1] {ECO:0000313|EMBL:ABF97758.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG Rice Chromosome 3 Sequencing Consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S., Luo M.,
RA Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G.,
RA Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2] {ECO:0000313|EMBL:ABF97758.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell R., Wing R.A., McCombie W.A., Ouyang S.;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DP000009; ABF97758.1; -; Genomic_DNA.
DR AlphaFoldDB; Q10GE4; -.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR45835:SF87; RNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR45835; YALI0A06105P; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF08284; RVP_2; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 2.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 124..137
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 717..884
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 91..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1090 AA; 124639 MW; 0E98446AB7570A54 CRC64;
MASKLKSMEM EISKGFLVHF IMSSLPQEFS PFTINYNAMK IKWGIDELIA MYVQEEERLK
AERVDHANLF KHSKKKKYKK FKKEYLKPKP SQFKEKGQSS NQSQQNKSGG NPYTEEKGKE
KDGCYFCGKS GHRQKDCIGF MRWLSKKDTD VISFVDESLN IDYATNSWWI DSGATIHVAN
SLQGFAMRRT LRRGERRIRV ANGERISTHG DCQRGPLGCK RACPGEGGTL QYYSPAVPIE
IQGIPFPSDL ILLDTKNLDV ILGMNWLAQF QGVVDCARRT VTLYRGLEQP VVFFAPPTSV
GSSELHQIGL SETPIVREFR DVFPEELPGM PPKREIEFRI DLAPGTTPLY KRPYRMAANE
LAEVKKQLEE LKEKGGRPSA ASPSGVGKVA GTPTVCKLSK CEFWLSEVKF LGHVISTKGV
AVDPETVTAV TDWKQPKIVT QVRSFLGLAG YYRRFIENFS KIARPMTQLL KKEEKFVWSP
QCEKAFQTLH EKLVSSPVLI LPDTRKDYLV YCDASRQGLG CVLMQEGHVV AYASRQLRPH
EGNYPTHDLE LAAVVHALKI WRHYLIGNRC EIYTDHKSLK YIFTQSDLNL RQRRWLELIK
DYDVGIRYHP GKANVVADAL SRKSRCNTLG VRGIPPELHQ QMEALNLSIV GRGFLAMLEA
KPTLLDQIRE AQKNDPDMHG ILKNMKQGKA AGFTEDEHGT LWNGNRRVKA EHQRPARLLQ
PLQVPEWKWD EIGMDFITGL PKTQGGHDSI WVVVDRLTKV ARFIPVKTTY GGNKLAELYF
ARIVSLHGVP KKIVSDRGSQ FTSHFWKKLQ EELGTRLNFS TAYHPQTDGQ TERLNQILED
MLRACVLDFE KTWDKSLPYA EFSYNNSYQA SIQMAPYEAL YGRKCRTPLL WDQVGESQVF
GTDILREAEA KVRTIWDNLK VAQSRQKSYA DNRRRNLEFA VDDFVYLRVT PLRGVDRFQT
KGKLAPRFVG PFRIIARRGE VAYQLELPAS LGNVHDVFHV SQLKKCLRVP SEQADSEQIE
VREDLTYVER LVKILDTMER RTRNRVIRFC KVQWSNNAEE EATWERESEL KAAHPDLFAS
SSESRGRDSV
//
