ID Q12CQ4_POLSJ Unreviewed; 509 AA.
AC Q12CQ4;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=TRAP transporter large permease protein {ECO:0000256|RuleBase:RU369079};
GN OrderedLocusNames=Bpro_1752 {ECO:0000313|EMBL:ABE43688.1};
OS Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=296591 {ECO:0000313|EMBL:ABE43688.1, ECO:0000313|Proteomes:UP000001983};
RN [1] {ECO:0000313|Proteomes:UP000001983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS666 / ATCC BAA-500 {ECO:0000313|Proteomes:UP000001983};
RX PubMed=18723656; DOI=10.1128/AEM.00197-08;
RA Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA Stothard P., Coleman N.V.;
RT "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT relevance to biotechnology.";
RL Appl. Environ. Microbiol. 74:6405-6416(2008).
CC -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC transport system. {ECO:0000256|RuleBase:RU369079}.
CC -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC protein and the two transmembrane proteins.
CC {ECO:0000256|RuleBase:RU369079}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU369079}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU369079}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TRAP transporter large permease family.
CC {ECO:0000256|RuleBase:RU369079}.
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DR EMBL; CP000316; ABE43688.1; -; Genomic_DNA.
DR RefSeq; WP_011482687.1; NC_007948.1.
DR AlphaFoldDB; Q12CQ4; -.
DR STRING; 296591.Bpro_1752; -.
DR KEGG; pol:Bpro_1752; -.
DR eggNOG; COG4664; Bacteria.
DR HOGENOM; CLU_019824_3_0_4; -.
DR OrthoDB; 9796052at2; -.
DR Proteomes; UP000001983; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR010656; DctM.
DR InterPro; IPR004681; TRAP_DctM.
DR NCBIfam; TIGR00786; dctM; 1.
DR PANTHER; PTHR33362; SIALIC ACID TRAP TRANSPORTER PERMEASE PROTEIN SIAT-RELATED; 1.
DR PANTHER; PTHR33362:SF7; SLL1103 PROTEIN; 1.
DR Pfam; PF06808; DctM; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU369079};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369079};
KW Reference proteome {ECO:0000313|Proteomes:UP000001983};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369079};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369079}; Transport {ECO:0000256|RuleBase:RU369079}.
FT TRANSMEM 6..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 55..79
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 105..133
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 145..168
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 188..205
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 225..244
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 256..275
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 296..317
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 337..365
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 377..405
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 425..446
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT DOMAIN 12..448
FT /note="TRAP C4-dicarboxylate transport system permease DctM
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF06808"
FT REGION 473..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 509 AA; 55008 MW; D81BD97137409897 CRC64;
MQMENFAPIM FAGLVLIMLI GFPVAFSLAA LGLGSGFLAI QMGWFPASFM SNLPLNMFGI
LSNELLLAIP FFTFMGAILE KCGLAEDMLD SMGQLFGPAK GGLGYSVIIV GFILGAITGT
VAGQVIAMAL ISLPVMIRYG YNMRYATGVL AASGTITQLV PPSLVLIVMA DQLGRSVGDM
YKGAWGPSIL QVLIFAGYTF MLGVFKPHHV PGVPKDARTL NGWPLWAKCL RGIIPSAILI
FAVLGSMGGL PGINTAIATP TEAGAMGVVG ALILAAMHKR LTRALIWEAM VGTMRLTAMV
VFILIGARVF SMVFQGVDGA KWVEHMLSGL PGGQTGFLIA VNLFIFFLAF FLDFFEIAFI
ILPMLGPVAD KLGIDLIWFG VLLCVNMQTS FMHPPFGFAL FYLRGIADTL FKEGRIPQAI
KSSDIYLGAI PWVAMQLVLV TIVIFVPQTV TVFLDKEEKI DIDKVKIEMP AEAIDDKPAE
LNPGETQGQR DTQNADDEQK KIDDLFNKK
//
