ID Q12H94_POLSJ Unreviewed; 808 AA.
AC Q12H94;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Transporter, putative {ECO:0000313|EMBL:ABE42098.1};
GN OrderedLocusNames=Bpro_0133 {ECO:0000313|EMBL:ABE42098.1};
OS Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=296591 {ECO:0000313|EMBL:ABE42098.1, ECO:0000313|Proteomes:UP000001983};
RN [1] {ECO:0000313|Proteomes:UP000001983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS666 / ATCC BAA-500 {ECO:0000313|Proteomes:UP000001983};
RX PubMed=18723656; DOI=10.1128/AEM.00197-08;
RA Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA Stothard P., Coleman N.V.;
RT "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT relevance to biotechnology.";
RL Appl. Environ. Microbiol. 74:6405-6416(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000316; ABE42098.1; -; Genomic_DNA.
DR RefSeq; WP_011481108.1; NC_007948.1.
DR AlphaFoldDB; Q12H94; -.
DR STRING; 296591.Bpro_0133; -.
DR KEGG; pol:Bpro_0133; -.
DR eggNOG; COG1033; Bacteria.
DR HOGENOM; CLU_008861_4_0_4; -.
DR OrthoDB; 9176717at2; -.
DR Proteomes; UP000001983; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF10; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001983};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 641..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 663..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 691..714
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 734..755
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 767..791
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 282..400
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 808 AA; 87439 MW; EBF15020113844AC CRC64;
MHADSSSINA SSQPVVARLE DFDTRSGTLL ERAFFNHRPW VMALCLLLTL VLGWQATKLQ
LNASFEKTIP TSHPYIVNYL AHKGDLAGQG NALRLVVQAK KGTIFDKRYL DALQKINDEI
FLLPGVDRPF MKSLWTSNTR WVAVTEEGLD GGPVIPDVYD GSAASLADLR ANVERSGEIG
QLVAGDFKSS IVFVPLLDRN PETGKALDYG DLSRQIEVLR ARYGSDTLEI GVTGFAKVVG
DLIEGLQQVL LFFLLALAIT TMVLFAYTRC GRSTALVVAC SLVAVVWQFG LLALLGYELD
PYSVLVPFLV FAIGMSHGAQ KMNGIMQDIG RGTHRVVAAR YTFRRLFMAG LTALLCDAVG
FAVLVIIQIK VIQDLALIAS IGVAVLIFTN LVLLPILLSY TGVAPSAAAR SLREETVQAG
ARRPWLWALL DHFTQKRWAT AAIVVSGLMA AGGYAVSVNL KIGDLDPGAS ELRADSRYNR
DNAYQISHYA ASADILTVMV TTPVDQCTSY GTLARLDSLA WGLEQLPGVE STNSMAALSR
LAMVGYNEGN FKWFELLPND GALGGVQTRA PRELFNQNCS FLALYVYLKD HKAETLSRVV
AEVEKFAAAN NTPEVTFKLA AGSAGIDAAT NIVVGKAMQE MLLWVYAAVV VLCWITFRSW
RAVVVAVLPL VLTSILCEAL MVWLGMGVKV ATLPVIALGV GIGVDYALYV LSITLARMRE
GASLSDAYHH ALQFTGRVVM LTGITLALAV GTWAFSPIKF QADMGILLAF MFVWNMVGAL
VLLPALGHFL LRKPVVAVVA PAAISVSI
//
