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Database: UniProt
Entry: Q12R91
LinkDB: Q12R91
Original site: Q12R91 
ID   TRMN6_SHEDO             Reviewed;         265 AA.
AC   Q12R91;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   29-OCT-2014, entry version 58.
DE   RecName: Full=tRNA1(Val) (adenine(37)-N6)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
DE            EC=2.1.1.223 {ECO:0000255|HAMAP-Rule:MF_01872};
DE   AltName: Full=tRNA m6A37 methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
GN   OrderedLocusNames=Sden_0745;
OS   Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=318161;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OS217 / ATCC BAA-1090 / DSM 15013;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of Shewanella denitrificans OS217.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the adenine in position 37 of
CC       tRNA(1)(Val) (anticodon cmo5UAC). {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + adenine(37) in
CC       tRNA(1)(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenine(37)
CC       in tRNA(1)(Val). {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. tRNA
CC       (adenine-N(6)-)-methyltransferase family. {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
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DR   EMBL; CP000302; ABE54035.1; -; Genomic_DNA.
DR   RefSeq; WP_011495200.1; NC_007954.1.
DR   RefSeq; YP_561758.1; NC_007954.1.
DR   ProteinModelPortal; Q12R91; -.
DR   STRING; 318161.Sden_0745; -.
DR   DNASU; 4016851; -.
DR   EnsemblBacteria; ABE54035; ABE54035; Sden_0745.
DR   GeneID; 4016851; -.
DR   KEGG; sdn:Sden_0745; -.
DR   PATRIC; 23487170; VBISheDen79529_0792.
DR   eggNOG; COG4123; -.
DR   HOGENOM; HOG000283147; -.
DR   KO; K15460; -.
DR   OMA; KALCQPF; -.
DR   OrthoDB; EOG66TGB2; -.
DR   BioCyc; SDEN318161:GHKQ-770-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   GO; GO:0016430; F:tRNA (adenine-N6-)-methyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   HAMAP; MF_01872; tRNA_methyltr_YfiC; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases-like.
DR   InterPro; IPR022882; tRNA_adenine-N6_MeTrfase.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; Reference proteome;
KW   S-adenosyl-L-methionine; Transferase; tRNA processing.
FT   CHAIN         1    265       tRNA1(Val) (adenine(37)-N6)-
FT                                methyltransferase.
FT                                /FTId=PRO_0000387419.
SQ   SEQUENCE   265 AA;  28361 MW;  6C40F5C8440A6589 CRC64;
     MAFTFKQFHI DDGQCAMAVS TDGVLLGAYA PLTQAKSVLD IGAGSGLLSL MAAQRTQADC
     QIVAIELDQN AANACQNNVN NSPWSKRIKV VNSSIQAYCD DLASLSSQVD NQTAAITPTS
     KFDYIISNPP FFENGPSSQS PERAAARHTH NLPFSALFNA IKSLLSPLGL STIILPVQSL
     ESATLAYQEA GLKLSCQRFI ASVQGKSPYR VILCLQHLSA GDILLALGAG KSLNPLSETS
     LFIRDNQGQF GPEMASLCKD FYLKL
//
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