ID Q12UG1_METBU Unreviewed; 592 AA.
AC Q12UG1;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=RNA-directed DNA polymerase {ECO:0000313|EMBL:ABE52915.1};
DE EC=2.7.7.49 {ECO:0000313|EMBL:ABE52915.1};
GN OrderedLocusNames=Mbur_2039 {ECO:0000313|EMBL:ABE52915.1};
OS Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 /
OS ACE-M).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX NCBI_TaxID=259564 {ECO:0000313|EMBL:ABE52915.1, ECO:0000313|Proteomes:UP000001979};
RN [1] {ECO:0000313|Proteomes:UP000001979}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6242 / NBRC 107633 / OCM 468 / ACE-M
RC {ECO:0000313|Proteomes:UP000001979};
RX PubMed=19404327; DOI=10.1038/ismej.2009.45;
RA Allen M.A., Lauro F.M., Williams T.J., Burg D., Siddiqui K.S.,
RA De Francisci D., Chong K.W., Pilak O., Chew H.H., De Maere M.Z., Ting L.,
RA Katrib M., Ng C., Sowers K.R., Galperin M.Y., Anderson I.J., Ivanova N.,
RA Dalin E., Martinez M., Lapidus A., Hauser L., Land M., Thomas T.,
RA Cavicchioli R.;
RT "The genome sequence of the psychrophilic archaeon, Methanococcoides
RT burtonii: the role of genome evolution in cold adaptation.";
RL ISME J. 3:1012-1035(2009).
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DR EMBL; CP000300; ABE52915.1; -; Genomic_DNA.
DR AlphaFoldDB; Q12UG1; -.
DR STRING; 259564.Mbur_2039; -.
DR KEGG; mbu:Mbur_2039; -.
DR HOGENOM; CLU_013584_15_4_2; -.
DR Proteomes; UP000001979; Chromosome.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR CDD; cd00085; HNHc; 1.
DR CDD; cd01651; RT_G2_intron; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR025960; RVT_N.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF8; GROUP II INTRON-ASSOCIATED OPEN READING FRAME; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13655; RVT_N; 1.
DR SMART; SM00507; HNHc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:ABE52915.1};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:ABE52915.1};
KW Transferase {ECO:0000313|EMBL:ABE52915.1}.
FT DOMAIN 126..366
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 592 AA; 68043 MW; D44444C0D2896584 CRC64;
MQTYSMVSKR MNEGITMNVR ISNTPNNEAE ALSGHAELNG EKLTDMLNWN FINWSSVESH
VNRIQVRITK AVINKNWNLV KKLSYLLTHS HYAKLLAVRK VIRNKGRRTA GIDGEFWSTP
VSKVNAARSL SDKRYKAKPL KRIFIEKYGS DKKRPLGIPT MYDRAMQALY ALALDPIAEV
TADKRSFGFR KFRSTHDACS QIFGTISKKD SAQCILEGDI KGCFDNISHQ WLIDNIPMDK
SILKQFLKAG FVYENSLFPT KAGTPQGGII SPILANMTLD GIEGVLADKY HRGVSGKITT
RQRAKHKVNF VRYADDFIVT AKTKEIAEEA KELIKNFLTD RGLELSDEKT LITHIDDGFD
FLGWNVRKYK GKLLIKPSKK SIKKVTEKIS NTIKDGKTWT QEDLISKLNP IITGWSNYHQ
GVASKETFSL IDFKIWNILW KWAKRRHPMK SRTWIAHKYW HPKGTRKWVF STMKNQLKLM
SDKMIVRNPQ IKLDKNPYTD TEYFVERKLN QGSKKLLGKF KTVWKNQKGK CPFCNLLIDI
NNGGEERPLH HKNGNHDDNG ITNLVYAHVY CHRQYHANNP KITVARQGLR DA
//
