ID Q12YS5_METBU Unreviewed; 309 AA.
AC Q12YS5;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Cysteine synthase {ECO:0000313|EMBL:ABE51401.1};
DE EC=2.5.1.47 {ECO:0000313|EMBL:ABE51401.1};
GN OrderedLocusNames=Mbur_0413 {ECO:0000313|EMBL:ABE51401.1};
OS Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 /
OS ACE-M).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX NCBI_TaxID=259564 {ECO:0000313|EMBL:ABE51401.1, ECO:0000313|Proteomes:UP000001979};
RN [1] {ECO:0000313|Proteomes:UP000001979}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6242 / NBRC 107633 / OCM 468 / ACE-M
RC {ECO:0000313|Proteomes:UP000001979};
RX PubMed=19404327; DOI=10.1038/ismej.2009.45;
RA Allen M.A., Lauro F.M., Williams T.J., Burg D., Siddiqui K.S.,
RA De Francisci D., Chong K.W., Pilak O., Chew H.H., De Maere M.Z., Ting L.,
RA Katrib M., Ng C., Sowers K.R., Galperin M.Y., Anderson I.J., Ivanova N.,
RA Dalin E., Martinez M., Lapidus A., Hauser L., Land M., Thomas T.,
RA Cavicchioli R.;
RT "The genome sequence of the psychrophilic archaeon, Methanococcoides
RT burtonii: the role of genome evolution in cold adaptation.";
RL ISME J. 3:1012-1035(2009).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP000300; ABE51401.1; -; Genomic_DNA.
DR RefSeq; WP_011498563.1; NC_007955.1.
DR AlphaFoldDB; Q12YS5; -.
DR STRING; 259564.Mbur_0413; -.
DR GeneID; 3997922; -.
DR KEGG; mbu:Mbur_0413; -.
DR HOGENOM; CLU_021018_1_0_2; -.
DR OrthoDB; 10138at2157; -.
DR Proteomes; UP000001979; Chromosome.
DR GO; GO:0004124; F:cysteine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR005856; Cys_synth.
DR InterPro; IPR005859; CysK.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01139; cysK; 1.
DR NCBIfam; TIGR01136; cysKM; 1.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF194; CYSTATHIONINE BETA-SYNTHASE; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 4: Predicted;
KW Transferase {ECO:0000313|EMBL:ABE51401.1}.
FT DOMAIN 8..295
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 309 AA; 32888 MW; D45FF2F4E0504CED CRC64;
MENIYEDITK TVGKTPLVRL NRITVGCYAT VLVKVEAFNP LGSIKDRIAL NMIETAEKDG
MLKKGAIVIE PTSGNTGIGL AFVCATKGYR LILTMPETMS VERRNILKVL GAEIVLTPGP
NGMKGAIEEA ERIGKETPDS FIPHQFMNPA NPDIHRCTTA GEIWDDTGGK VDILVAGVGT
GGTITGVSEE LKSRKPGFKA IAVEPKDSAV LSGGSPGPHM IQGIGAGFVP DVLNVDIIDE
IITVSNEDAF ETTRELAKKE GILAGISSGA ALFAALDVAR RKENEGKMIV VVLPDTGERY
LSTTIVEKE
//
