ID Q14LP1_SPICI Unreviewed; 207 AA.
AC Q14LP1;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Deoxyadenosine/deoxycytidine kinase {ECO:0000313|EMBL:APE74494.1};
DE SubName: Full=Deoxynucleoside kinase {ECO:0000313|EMBL:CAK99589.1, ECO:0000313|EMBL:QIA72665.1};
DE EC=2.7.1.- {ECO:0000313|EMBL:CAK99589.1};
GN Name=yaaF {ECO:0000313|EMBL:CAK99589.1};
GN Synonyms=dck {ECO:0000313|EMBL:APE74494.1};
GN ORFNames=GL982_02965 {ECO:0000313|EMBL:QIA72665.1}, HHA36_03020
GN {ECO:0000313|EMBL:QJU61457.1}, SCITRI_00598
GN {ECO:0000313|EMBL:APE74494.1}, SPICI17_004
GN {ECO:0000313|EMBL:CAK99589.1};
OS Spiroplasma citri.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC Spiroplasma.
OX NCBI_TaxID=2133 {ECO:0000313|EMBL:CAK99589.1};
RN [1] {ECO:0000313|EMBL:CAK99589.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GII3-3X {ECO:0000313|EMBL:CAK99589.1};
RA Carle P., Saillard C., Carrere N., Carrere S., Duret S., Eveillard S.,
RA Gaurivaud P., Gourgues G., Gouzy J., Salar P., Verdin E., Breton M.,
RA Blanchard A., Laigret F., Bove J.M., Renaudin J., Foissac X.;
RT "Partial chromosome sequence of Spiroplasma citri reveals extensive viral
RT invasion and important gene decay.";
RL Appl. Environ. Microbiol. 76:3420-3426(2010).
RN [2] {ECO:0000313|EMBL:APE74494.1, ECO:0000313|Proteomes:UP000183717}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R8-A2 {ECO:0000313|EMBL:APE74494.1,
RC ECO:0000313|Proteomes:UP000183717};
RA Davis R.E., Shao J., Gasparich G., Gaynor B., Donofrio N.;
RT "Complete Genome Sequence of Spiroplasma citri R8A2.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QIA72665.1, ECO:0000313|Proteomes:UP000464221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BLH-13 {ECO:0000313|EMBL:QIA72665.1,
RC ECO:0000313|Proteomes:UP000464221};
RA Yokomi R., Chen J., Rattner R., Selvaraj V., Maheshwari Y., Osman F.,
RA Vidalakis G.;
RT "Whole genome sequencing and comparative genomics analyses of six strains
RT of Spiroplasma citri.";
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:QJU61457.1, ECO:0000313|Proteomes:UP000501133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 {ECO:0000313|EMBL:QJU61457.1,
RC ECO:0000313|Proteomes:UP000501133};
RA Rattner R., Dang T., Mello A.F.S., Espindola A.S., Cardwell K.,
RA Fletcher J., Yokomi R., Vidalakis G.;
RT "Genome-wide analyses of Spiroplamsa citri strains and comparison with
RT other spiroplasmas.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP013197; APE74494.1; -; Genomic_DNA.
DR EMBL; AM285318; CAK99589.1; -; Genomic_DNA.
DR EMBL; CP047428; QIA72665.1; -; Genomic_DNA.
DR EMBL; CP053304; QJU61457.1; -; Genomic_DNA.
DR RefSeq; WP_004572355.1; NZ_CP096808.1.
DR AlphaFoldDB; Q14LP1; -.
DR STRING; 2133.SCITRI_00598; -.
DR GeneID; 54238515; -.
DR KEGG; sck:SCITRI_00598; -.
DR OrthoDB; 9776634at2; -.
DR Proteomes; UP000183717; Chromosome.
DR Proteomes; UP000464221; Chromosome.
DR Proteomes; UP000501133; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002624; DCK/DGK.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000705; DNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Kinase {ECO:0000313|EMBL:CAK99589.1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Transferase {ECO:0000313|EMBL:CAK99589.1}.
FT DOMAIN 3..187
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
FT ACT_SITE 77
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT BINDING 31
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 43
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 54
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 78
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 83
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 138..142
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 147
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 183..185
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
SQ SEQUENCE 207 AA; 24787 MW; 6FAFF6BF759AA9D2 CRC64;
MKIAVFGTVG AGKTKVSEEL CKQLNYNLFK EPLEENPYFK DFYQDMEGFA FKMQIYMLTT
RIEQFFNIDN LDDTVFDRTI LEDPVFVRVS HLLKIMNEID FKVYNRFFQN VIVPILKQKL
GFDVIIYLKV STEKAVERIK QRGRQLELET PYYYWEKLNE QYEILYHELK NDYKFIVIDA
DNDDFSEKIS IIMQHLLPLD NKVPCLI
//
