ID Q162S0_ROSDO Unreviewed; 1770 AA.
AC Q162S0;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=ATP-dependent DNA helicase, UvrD/REP family domain {ECO:0000313|EMBL:ABG33023.1};
GN OrderedLocusNames=RD1_3542 {ECO:0000313|EMBL:ABG33023.1};
OS Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp.
OS (strain OCh 114)) (Roseobacter denitrificans).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseobacter.
OX NCBI_TaxID=375451 {ECO:0000313|EMBL:ABG33023.1, ECO:0000313|Proteomes:UP000007029};
RN [1] {ECO:0000313|EMBL:ABG33023.1, ECO:0000313|Proteomes:UP000007029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33942 / OCh 114 {ECO:0000313|Proteomes:UP000007029};
RX PubMed=17098896; DOI=10.1128/JB.01390-06;
RA Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J., Ramos H.,
RA Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C., Shah M.K.,
RA O'huallachain M.E., Lince M.T., Blankenship R.E., Beatty J.T.,
RA Touchman J.W.;
RT "The complete genome sequence of Roseobacter denitrificans reveals a
RT mixotrophic rather than photosynthetic metabolism.";
RL J. Bacteriol. 189:683-690(2007).
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DR EMBL; CP000362; ABG33023.1; -; Genomic_DNA.
DR STRING; 375451.RD1_3542; -.
DR KEGG; rde:RD1_3542; -.
DR eggNOG; COG0210; Bacteria.
DR eggNOG; COG0514; Bacteria.
DR HOGENOM; CLU_002862_0_0_5; -.
DR Proteomes; UP000007029; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd18018; DEXHc_RecQ4-like; 1.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000007029}.
FT DOMAIN 375..552
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 578..732
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1159..1373
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 1180..1187
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1770 AA; 194756 MW; 90AA7FAB78076CB1 CRC64;
MTRYSLPRLR RPASRRVSLP VQCQDFCRLR FPREAICATA AKGRKRSWRK AIACTQLKKA
FNCFELRGFV EMGSHHQAFL ARCLSIDIEV DPGSAIVFGL AAVRVDGPAI PKRTKGLQKR
DLDALHQALE NVSHPLGHNI LSHDLPHLAA LRPDLPVTGA IDTLWLNPLA FPRNPYHHLV
KHYQDGRLAT GHINDPEQDA LLVFDVLDNQ LEAFGALHKS NPDALACYHY LTTRAEGMTG
FDAVFRYIRG HDCPSQTEAQ DALVRMLAGQ VCGARLAQTL ERLSSPKNGW PMAYALAWIT
VAGGDSVMPP WVRAQFRKAS LIVKHLRDTS CGDPNCAWCA EQNDPLRALQ KWFGFEAYRP
QPVDPEGRPL QERIVDEAMS GKSVLGILPT GTGKSVCYQV PALSRFDKTG ALTVVISPLV
ALMADQVQGM ERAGLTCAVT INGMLSMPER QDALDKVRLG EAGILIISPE QLRSTAVRSV
LAQREVGLWA IDEAHCLSKW GHDFRPDYRY LGRFIREFSG DQPPAPIICL TATAKPEVVA
EIVEHFRARL DVPLTVLDGG STRQNLTFDV RPTTKTTKLA DVLSVIEQSL PSEGRSGAVV
YCASRKSTER VAEFLKAQGL DAAHFHAGLS PDDKQTVQER FRIGDLRVIA ATNAFGMGID
KPDIRLVVHA DIPGSLENYL QEAGRAGRDR LHANCVLLYA TDDVERQFGL TSSARLARHE
IGAILKALRR IDDKTQKSGA VVATAGEIVR HEKDQDFERD SATDDTRVKT AVSWLEEAQL
LSREENRVRI FPSSLTVRSL AEAKTKLAGA KITMAHRNAL LAIVRHLIQA AADEGVSTDS
LCGVAGLTPG ALTKALVTLE TLGIARNDMA LTAFVHVGVA DASIARLGKI TGLERDLIAQ
MQELAPDADA QTPQPLNLPE ACTALRSQGH HDVRPDQIDK LLRGMARDGR DLDGGTGNLR
LRKASRKTLM VTLLRPWRSI ARTAEVRHVA ASLLLSHLIE KLAKGTRGKD LQVETTYGDL
LAAVAQDAFL KTSGVADMTR LMERALLWLH EQGVLNLGKG LTVFRQAMTV HLNPKGGQFT
QVHFTPLEEH YAEQTLQTHV MAHYAETGLV AMPDAMRLSE DYFLLTQDQF MKRWMPGKAR
ELRRQTTSAS WKKIVEDLGN KTQESIVADD RASTNVLVLA GPGSGKTRVL VHRVAYLLRI
KREDPRGILV LAYNRHAASE IRTRLAALVG EDARGVTICT CHALAMRLVG ASFSGFDAQN
ADFDRIVTDA AGLLNGDGLS KSEAEAQRDS LLDGYRWILV DEYQDIGPEE YALISAVAGR
SLEDADLKLS LFAVGDDDQN IYAFTGASVD FIRQFEADYH ARPSFLIENY RSTAHIIAAS
NSVIEPAPGR MKAEQAIRIN AARSVGNPGG RMADADPVAQ GRVQLLDVPP GPKPQAIAAI
DELLRLCALD PQWDWRKAAV ISRDWKSLDA VRSYAEAKGI SVDMANEDLP TIWRLRETQA
FVAALRAKGS ELLGLNDILA ALNALQASKW TELLAEGIAD LARELQDKTM PAPDVIEWIA
EWARDTRGAQ RGLLLTTAHR AKGLEFDHVV ILNGGWDRAS QNEDAAAPRR LFYVAMTRAR
HSLAVMTSGT HALLTSKGDA TLRRALTPRD SESHGPEKVF QLPSLKSVDL SYAGRKGSDD
PVHAAIRDAQ TGDDITLEYR ASRWVILDKN SRALARMAKN WKPPEGSSFL SGTLGAIVIW
RKTDSQEEFQ RHIKQDEWET VLPELVFVAP
//
